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Merck

A5040

Ethyl 3-aminobenzoate methanesulfonate salt

analytical standard

Sinónimos:

MS-222, Tricaine

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About This Item

Fórmula empírica (notación de Hill):
C9H11NO2 · CH4SO3
Número CAS:
886-86-2
Peso molecular:
261.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329770864
EC Number:
212-956-8
Beilstein/REAXYS Number:
3775022
MDL number:
MFCD00013176

Nombre del producto

Ethyl 3-aminobenzoate methanesulfonate salt, analytical standard

InChI key

FQZJYWMRQDKBQN-UHFFFAOYSA-N

InChI

1S/C9H11NO2.CH4O3S/c1-2-12-9(11)7-4-3-5-8(10)6-7;1-5(2,3)4/h3-6H,2,10H2,1H3;1H3,(H,2,3,4)

SMILES string

CS(O)(=O)=O.CCOC(=O)c1cccc(N)c1

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

~148 °C

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

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Application

Ethyl 3-aminobenzoate methanesulfonate analytical standard can be used as follows:

  • Preparation of an anti-TMS monoclonal antibody (mAb) for the analysis of tricaine in fish samples using a lateral-flow immunochromatographic strip (LF-ICS) method
  • Modified QuEChERS-based sample extraction of tricaine methanesulfonate from blood, muscle, and liver samples obtained from carp fish for its analysis by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)
  • Multi-residue detection of tricaine mesylate and malachite green in aquaculture water, fish, and shrimp samples using tricolor immunochromatographic test strip with double test lines (TS-DTL)
  • Analysis of water samples for MS-222 using solid phase extraction for sample treatment and liquid chromatography/tandem mass spectrometry (LC-MS/MS) for determination

General description

Ethyl 3-aminobenzoate methanesulfonate salt is a synthetic benzocaine derivative that belongs to the class of ester-type anaesthetics, widely used in aquacultures.

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
MKCZ0386
MKCX0634
MKCV6661
MKCR5826
MKCS5788

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Monica Bonetti et al.
PloS one, 9(4), e94884-e94884 (2014-04-17)
The PTPN11 (protein-tyrosine phosphatase, non-receptor type 11) gene encodes SHP2, a cytoplasmic PTP that is essential for vertebrate development. Mutations in PTPN11 are associated with Noonan and LEOPARD syndrome. Human patients with these autosomal dominant disorders display various symptoms, including
Wouter Koole et al.
Disease models & mechanisms, 7(7), 929-936 (2014-02-04)
Mosaic analysis, in which two or more populations of cells with differing genotypes are studied in a single animal, is a powerful approach to study developmental mechanisms and gene function in vivo. Over recent years, several genetic methods have been
Lomeli Carpio Shull et al.
Developmental biology, 461(2), 132-144 (2020-02-12)
The formation of the craniofacial skeleton is a highly dynamic process that requires proper orchestration of various cellular processes in cranial neural crest cell (cNCC) development, including cell migration, proliferation, differentiation, polarity and cell death. Alterations that occur during cNCC
B Ju et al.
Oncogenesis, 3, e96-e96 (2014-04-02)
Dysregulation of Sonic hedgehog (Shh) signaling has been implicated in glioma pathogenesis. Yet, the role of this pathway in gliomagenesis remains controversial because of the lack of relevant animal models. Using the cytokeratin 5 promoter, we ectopically expressed a constitutively
Sandra E Hernández et al.
Veterinary anaesthesia and analgesia, 39(6), 584-590 (2012-07-07)
Three anaesthetics (MS222, clove oil and a mixture of ketamine/diazepam) were administered to cane toads to determine their effect on the hypothalamic-pituitary-adrenal (HPA) axis. Time to induction and recovery and any adverse events were also evaluated. Prospective randomized experimental trial.
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Product Information Sheet - A5040

Product Information Sheet

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