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Merck

N6142

Nabumetone

analytical standard

Sinónimos:

4-(6-Methoxy-2-naphthyl)-2-butanone

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About This Item

Fórmula empírica (notación de Hill):
C15H16O2
Número CAS:
42924-53-8
Peso molecular:
228.29
NACRES:
NA.24
PubChem Substance ID:
329818660
UNSPSC Code:
41116107
MDL number:
MFCD00079518

Nombre del producto

Nabumetone, analytical standard

InChI

1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

SMILES string

COc1ccc2cc(CCC(C)=O)ccc2c1

InChI key

BLXXJMDCKKHMKV-UHFFFAOYSA-N

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Categorías relacionadas

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Nonselective non-steroidal anti-inflammatory drug (NSAID)

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCN3727
MKCG6105
MKCD9732
MKBZ6732V
MKBT7117V

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Jinhyun Kim et al.
Clinical therapeutics, 31(12), 2860-2872 (2010-01-30)
S-adenosylmethionine (SAMe) has antiinflammatory and analgesic effects and has been reported to ameliorate the pain and dysfunction of osteoarthritis (OA). The metabolism of SAMe can be affected by geographic or ethnic factors. However, its efficacy and tolerability versus NSAIDs have
Chao-Shun Yang et al.
Stem cells (Dayton, Ohio), 29(10), 1528-1536 (2011-09-08)
Recent breakthroughs in creating induced pluripotent stem cells (iPSCs) provide alternative means to obtain embryonic stem-like cells without destroying embryos by introducing four reprogramming factors (Oct3/4, Sox2, and Klf4/c-Myc or Nanog/Lin28) into somatic cells. iPSCs are versatile tools for investigating
Pseudoseptic arthritis due to acute lipoarthrosis in a systemic lupus erythematosus patient with osteonecrosis.
Robert W Ike et al.
Arthritis and rheumatism, 61(8), 1130-1132 (2009-08-01)
Markku Kerola et al.
Basic & clinical pharmacology & toxicology, 104(1), 17-21 (2009-01-21)
: The beneficial actions of non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with inhibition of cyclooxygenase-2 (COX-2), whereas some of their adverse effects are associated mainly with inhibition of COX-1. Selective COX-2 inhibitors reduce the risk of gastrointestinal adverse events
Tatsuhiro Yoshida et al.
Journal of neurosurgery. Spine, 9(5), 411-418 (2008-11-04)
Neurotropin is a nonprotein extract from the inflamed skin of rabbits inoculated with vaccinia virus. In the present study the authors sought to clarify the focal antiinflammatory effects of Neurotropin in intervertebral disc cells, and these effects were compared with
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