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T0071000

Terfenadine

Name: Terfenadine
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol

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Fórmula empírica (notación de Hill):

C₃₂H₄₁NO₂

Número CAS:

50679-08-8

Peso molecular:

471.67

NACRES:

NA.24

PubChem Substance ID:

329826584

UNSPSC Code:

41116107

MDL number:

MFCD00079622

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Propiedades

grade

pharmaceutical primary standard

API family

terfenadine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4

InChI

1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3

InChI key

GUGOEEXESWIERI-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Terfenadine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Non-sedating second generation H1 histamine receptor antagonist.

Non-sedating second generation H1 histamine receptor antagonist. Mainly metabolized by Cyp3A4, 5, 7. Inhibits CYP2C8.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c