44611
Durcupan™ ACM
single component A, M epoxy resin
Sinónimos:
ACM resins
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impurities
bisphenol A epoxy resin
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General description
Awater-soluble embedding medium for EM based on an aliphatic polyepoxide.
Application
Durcupan™ACM, single component A, M epoxy resin has been used for:
- A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures.: This study presents a technique using Durcupan ACM for preparing large resin sections, enhancing the analysis of myelinated axons in rodent central and peripheral nervous systems.
- Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues.: This research utilizes Durcupan ACM in electron microscopy to create 3D models of neural tissues, facilitating studies via immersive virtual reality.
- Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR.: Explores the cardiovascular effects in rats using Durcupan ACM embedded samples for detailed tissue analysis.
- Embedding material for electron microscopy on the basis of Araldite®.
Features and Benefits
Mixtures of Durcupan ACM present an interesting alternative to methacrylates for embedding sections for electron microscopy. They present the advantage that they harden uniformly, practically without shrinkage. All fixing agents normally used for electronmicroscopic work are also suitable for the Durcupan ACM embedding process. This process consists of three phases: dehydration of the tissue with acetone or ethyl alcohol, infiltration with the embedding agent, followed by hardening.
Legal Information
Araldite is a registered trademark of Huntsman Advanced Materials Inc.
Durcupan is a trademark of Sigma-Aldrich Chemie GmbH
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Warning
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Clase de almacenamiento
10 - Combustible liquids
flash_point_f
377.6 °F
flash_point_c
192 °C
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
hcodes
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A method to prepare large resin sections for counting myelinated axons in rodent CNS and PNS structures
Dzurjaskova Z, et al.
Neuroscience Letters, 750, 135767-135767 (2021)
Long-term effect of prazosin and losartan administration on blood pressure, heart, carotid artery, and acetylcholine induced dilation of cardiovascular system of young Wistar rats and SHR
Kristek F, et al.
General Physiology and Biophysics, 32(2), 235?243-235?243 (2013)
Three-dimensional immersive virtual reality for studying cellular compartments in 3D models from EM preparations of neural tissues
Cali C, et al.
The Journal of Comparative Neurology, 524(1), 23-38 (2016)
Tin Ki Tsang et al.
eLife, 7 (2018-05-12)
Electron microscopy (EM) offers unparalleled power to study cell substructures at the nanoscale. Cryofixation by high-pressure freezing offers optimal morphological preservation, as it captures cellular structures instantaneously in their near-native state. However, the applicability of cryofixation is limited by its
Lu Gan et al.
Frontiers in immunology, 8, 1507-1507 (2017-12-19)
Leptin is an adipocyte-derived hormone and maintains adipose function under challenged conditions. Autophagy is also essential to maintain cellular homeostasis and regulate characteristics of adipose tissue. However, the effects of leptin on autophagy of adipocyte remain elusive. Here, we demonstrated
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