A9512

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate

Name: <SC>L-</SC>(−)-Norepinephrine (+)-bitartrate salt monohydrate
Brand: SIGMA

≥99% (TLC), solid, vasoconstrictor

Sinónimos:

L-(−)-Noradrenaline (+)-bitartrate salt monohydrate

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About This Item

Fórmula empírica (notación de Hill):

C₈H₁₁NO₃ · C₄H₆O₆ · H₂O

Número CAS:

108341-18-0

Peso molecular:

337.28

UNSPSC Code:

12352200

PubChem Substance ID:

57653897

NACRES:

NA.77

MDL number:

MFCD00150449

Nombre del producto

L-(−)-Norepinephrine (+)-bitartrate salt monohydrate, ≥99%, solid

SMILES string

O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1

InChI key

LNBCGLZYLJMGKP-LUDZCAPTSA-N

assay

≥99%

form

solid

color

white

solubility

H₂O: 46 mg/mL

Quality Level

200

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Categorías relacionadas

Bioactive Small Molecule Agonists

Bioactive Small Molecules

Application

L-(-)-Norepinephrine (+)-bitartrate salt monohydrate has been used:

to infuse dogs to form a intracellular lipid accumulation model
to analyse the signaling involved in the up-regulation of monocarboxylate transporter 2 (MCT2) expression in cultured cortical neuron
in neurochemical preparation to study the response of gram-negative and gram-positive bacteria to norepinephrine
to study the roles of peripheral hormones on thyroid activity of turtles

Biochem/physiol Actions

Norepinephrine bitartrate plays an important role in in vivo and in vitro development of pathogenic and indigenous bacteria. It acts as a vasoconstrictor and adrenergic neurotransmitter.

Disclaimer

Light sensitive

pictograms

GHS06

signalword

Danger

hcodes

H300 + H310

pcodes

P262 - P264 - P280 - P301 + P310 - P302 + P352 + P310 - P361 + P364

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Oral

Clase de almacenamiento

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

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Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway

Chenal J and Pellerin L

Journal of Neurochemistry, 102(2), 389-397 (2007)

6-hydroxydopamine-mediated release of norepinephrine increases faecal excretion of Salmonella enterica serovar Typhimurium in pigs.

Gillian D Pullinger et al.

Veterinary research, 41(5), 68-68 (2010-07-09)

Salmonella enterica serovar Typhimurium is an animal and zoonotic pathogen of worldwide importance. In pigs, transport and social stress are associated with reactivation and spread of Salmonella Typhimurium infection. The stress-related catecholamine norepinephrine (NE) has been reported to activate growth

Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo

Szczepaniak LS, et al.

American Journal of Physiology. Endocrinology and Metabolism, 276(5), E977-E989 (1999)

Skin blood flow and local temperature independently modify sweat rate during passive heat stress in humans.

Jonathan E Wingo et al.

Journal of applied physiology (Bethesda, Md. : 1985), 109(5), 1301-1306 (2010-08-14)

Sweat rate (SR) is reduced in locally cooled skin, which may result from decreased temperature and/or parallel reductions in skin blood flow. The purpose of this study was to test the hypotheses that decreased skin blood flow and decreased local

Roles of thyroid, adrenal and pancreatic hormones on thyroid activity of the soft-shelled turtles Lissemys punctata punctata Bonnoterre

Ray PP, et al.

Folia Biologica (Krakow.), 54(3-4), 93-102 (2006)

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