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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
2
Servicio técnico
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Permítanos ayudarlebiological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
40 kDa
species reactivity
horse, rat, dog, pig, mouse, human
concentration
0.5 mg - 1 mg/mL
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RASSF7(8045)
General description
RASSF7 is a RAS association domain-containing protein that is needed for spindle formation during mitosis in neural tubes. RASSF7 also enhaces cell survival by blocking the MKK7/JNK signaling pathway.
Rabbit Anti-RASSF7 antibody recognizes rat, mouse, human, canine, and bovine RASSF7.
Rabbit Anti-RASSF7 antibody recognizes rat, mouse, human, canine, and bovine RASSF7.
Immunogen
Synthetic peptide directed towards the middle region of human RASSF7
Application
Rabbit Anti-RASSF7 antibody can be used for western blot (5 μg/ml) and IHC (4-8 μg/ml) applications.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: RVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQAL
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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S Takahashi et al.
Cell death and differentiation, 18(4), 645-655 (2011-02-01)
Members of the Ras-association domain family (RASSF) of proteins influence apoptosis and cell cycling but little is known about the mechanisms. Here, we show that RASSF7 interacts with N-Ras and mitogen-activated protein kinase kinase 7 (MKK7) to negatively regulate c-Jun
Victoria Sherwood et al.
Molecular biology of the cell, 19(4), 1772-1782 (2008-02-15)
Mitosis is a fundamental feature of all cellular organisms. It must be tightly regulated to allow normal tissue growth and to prevent cancer formation. Here, we identify a new protein that is required for mitosis. We show that the Ras