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Merck

AV34390

Anti-RASSF7 antibody produced in rabbit

IgG fraction of antiserum

Sinónimos:

Anti-C11orf13, Anti-HRAS1, Anti-HRC1, Anti-MGC126069, Anti-MGC126070, Anti-Ras association (RalGDS/AF-6) domain family 7

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NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
2
Servicio técnico
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

40 kDa

species reactivity

horse, rat, dog, pig, mouse, human

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RASSF7(8045)

General description

RASSF7 is a RAS association domain-containing protein that is needed for spindle formation during mitosis in neural tubes. RASSF7 also enhaces cell survival by blocking the MKK7/JNK signaling pathway.
Rabbit Anti-RASSF7 antibody recognizes rat, mouse, human, canine, and bovine RASSF7.

Immunogen

Synthetic peptide directed towards the middle region of human RASSF7

Application

Rabbit Anti-RASSF7 antibody can be used for western blot (5 μg/ml) and IHC (4-8 μg/ml) applications.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: RVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQAL

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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S Takahashi et al.
Cell death and differentiation, 18(4), 645-655 (2011-02-01)
Members of the Ras-association domain family (RASSF) of proteins influence apoptosis and cell cycling but little is known about the mechanisms. Here, we show that RASSF7 interacts with N-Ras and mitogen-activated protein kinase kinase 7 (MKK7) to negatively regulate c-Jun
Victoria Sherwood et al.
Molecular biology of the cell, 19(4), 1772-1782 (2008-02-15)
Mitosis is a fundamental feature of all cellular organisms. It must be tightly regulated to allow normal tissue growth and to prevent cancer formation. Here, we identify a new protein that is required for mitosis. We show that the Ras