C1006

Cytidine 5′-monophosphate disodium salt

Name: Cytidine 5′-monophosphate disodium salt
Brand: SIGMA

≥99%, synthetic, crystalline

Sinónimos:

C-5′-P, CMP

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About This Item

Fórmula lineal:

C₉H₁₂N₃O₈PNa₂

Número CAS:

6757-06-8

Peso molecular:

367.16

NACRES:

NA.51

PubChem Substance ID:

24892293

UNSPSC Code:

41106305

EC Number:

229-819-3

MDL number:

MFCD00064355

Nombre del producto

Cytidine 5′-monophosphate disodium salt, Sigma Grade, ≥99%, crystalline

InChI key

RCIPNLSOCXMZDD-UHFFFAOYSA-N

InChI

1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;

SMILES string

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O

biological source

synthetic

grade

Sigma Grade

assay

≥99%

form

crystalline

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

2-8°C

Quality Level

300

Categorías relacionadas

Biochemicals

Chemistry & Biochemicals

Nucleosides and Nucleotides

Phosphates

Biochem/physiol Actions

Cytidine monophosphate (CMP) serve as a nucleotide carrier for sugars.

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.

Application

Cytidine 5′-monophosphate disodium salt has been used:

in nucleotide stock solution
as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

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Electrokinetic identification of ribonucleotide monophosphates (rNMPs) using thermoplastic nanochannels.

Charuni A Amarasekara et al.

Journal of chromatography. A, 1638, 461892-461892 (2021-01-22)

With advances in the design and fabrication of nanofluidic devices during the last decade, there have been a few reports on nucleic acid analysis using nanoscale electrophoresis. The attractive nature of nanofluidics is the unique phenomena associated with this length

Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration

Vaur P, et al.

Faseb Journal (2017)

Nucleotides modify growth of selected intestinal bacteria in vitro

Sauer N, et al.

Livestock Science, 133(1), 161-163 (2010)

Carbohydrate Metabolism III: Glycoproteins, Glycolipids, GPI Anchors, Proteoglycans, and Peptidoglycans

Medical Biochemistry, 307-330 (2002)

Structure of Staphylococcus aureus cytidine monophosphate kinase in complex with cytidine 5'-monophosphate.

Balvinder Dhaliwal et al.

Acta crystallographica. Section F, Structural biology and crystallization communications, 62(Pt 8), 710-715 (2006-08-02)

The crystal structure of Staphylococcus aureus cytidine monophosphate kinase (CMK) in complex with cytidine 5'-monophosphate (CMP) has been determined at 2.3 angstroms resolution. The active site reveals novel features when compared with two orthologues of known structure. Compared with the

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