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Merck

C3633

Cystathionine

≥90% (HPLC)

Sinónimos:

DL,DL-allo-Cystathionine, S-(2-Amino-2-carboxyethyl)homocysteine

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About This Item

Fórmula lineal:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
Número CAS:
535-34-2
Peso molecular:
222.26
NACRES:
NA.26
PubChem Substance ID:
24892630
UNSPSC Code:
12352209
EC Number:
208-613-7
MDL number:
MFCD00136759

Nombre del producto

Cystathionine, ≥90% (HPLC)

InChI key

ILRYLPWNYFXEMH-UHFFFAOYSA-N

InChI

1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)

SMILES string

NC(CCSCC(N)C(O)=O)C(O)=O

assay

≥90% (HPLC)

form

powder

color

white to off-white

mp

281 °C (dec.)

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... BHMT(635)

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Categorías relacionadas

Biochem/physiol Actions

Cystathionine is an intermediate in the biosynthesis of the amino acid cysteine. Cystathionine is used as a substrate to differentiate and analyze cystathionine gamma-lyase(s).

Other Notes

A mixture of 4 stereoisomers; L-, D-, L-allo- and D-allo-cystathionine.

Preparation Note

Prepared by method of Stekol.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000441209
0000441209
0000437622
0000437621
0000437621

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Miriam M Cortese-Krott et al.
Antioxidants & redox signaling, 27(10), 684-712 (2017-04-12)
Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances:
Ruben Esse et al.
International journal of molecular sciences, 20(4) (2019-02-20)
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the metabolism of the essential amino acid methionine. Hcy is considered a risk factor for atherosclerosis and cardiovascular disease (CVD), but the molecular basis of these associations remains elusive. The
Shuai Yuan et al.
Antioxidants & redox signaling, 27(10), 634-653 (2017-04-12)
Hydrogen sulfide (H In light of the recent understanding of oxidized sulfide metabolite formation and reactivity, comparatively few studies have been reported comparing cellular biological and in vivo effects of H Additional studies regarding persulfide and polysulfide formation and molecular
Xu Cao et al.
Antioxidants & redox signaling, 31(1), 1-38 (2018-05-24)
Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous transmitter alongside nitric oxide and carbon monoxide. In
Qinghai Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(6), 2200-2213 (2018-09-27)
The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular endothelial cell dysfunction. Hydrogen sulfide (H2S) has been shown to have an anti-oxidative effect, but its mode
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