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C7602

L-Cystine

Name: <SC>L</SC>-Cystine
Brand: SIGMA

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

Sinónimos:

(R,R)-3,3′-Dithiobis(2-aminopropionic acid)

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Fórmula lineal:

[-SCH₂CH(NH₂)CO₂H]₂

Número CAS:

56-89-3

Peso molecular:

240.30

NACRES:

NA.26

PubChem Substance ID:

24892973

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-296-3

MDL number:

MFCD00064228

Beilstein/REAXYS Number:

1728094

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Propiedades

Nombre del producto

L-Cystine, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Quality Level

200

agency

meets EP testing specifications

product line

BioXtra

assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to off-white

mp

>240 °C (dec.) (lit.)

solubility

1 M HCl: 100 mg/mL

application(s)

peptide synthesis

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

Descripción

Application

L-Cystine has been used as a supplement in astroglial-conditioned media to culture cerebral astroglia. It has been used in several techniques, such as HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry (UHPLC-MS/MS), to differentiate BMAA (β-N-methylamino-L-alanine), the cyanobacterial neurotoxin, from other diamino acids.
L-Cystine has been used as a supplement in oocyte culture media to improve oocyte maturation and parthenogenesis of embryonic development.

Biochem/physiol Actions

Cystinuria is characterized with renal transport and excretion of L-Cystine. Cysteine is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Cysteine is a source of disulfide linkage in protein and is associated with sulfur transport. At physiological pH, cysteine undergoes rapid oxidation to form cystine. Reduced availability of cysteine or cystine, influences leukocyte metabolism. L-Cystine is necessary for oxygen production and LDL (low density lipoprotein) modification by arterial smooth muscle cells.

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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Contenido relacionado

Product Information Sheet - C7602

Distinguishing the cyanobacterial neurotoxin b-N-methylamino-L-alanine
(BMAA) from other diamino acids

S.A. Banack

Toxicon (2011)

Using cysteine/cystine to overcome oxidative stress in goat oocytes and embryos cultured in vitro

Zhengrong Zhou

Molecular Medicine Reports, 14(2) (2016)

Mutation of Ataxia?Telangiectasia Mutated is Associated with Dysfunctional Glutathione Homeostasis in Cerebellar Astroglia

Andrew Campbell

Glia, 64(2), 227-239 (2016)

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