F3917
Forskolina
For use in molecular biology applications
Sinónimos:
7β-Acetoxi-8,13-epoxi-1α,6β,9α-trihidroxilabd-14-en-11-ona, Coleonol, Colforsin
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About This Item
Nombre del producto
Forskolina, For use in molecular biology applications
InChI key
OHCQJHSOBUTRHG-KGGHGJDLSA-N
InChI
1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
SMILES string
CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
biological source
Coleus forskohlii
description
for activation of T cells
product line
BioReagent
assay
≥98% (HPLC)
form
powder
mol wt
410.50 g/mol
color
white to off-white
solubility
ethanol: soluble
suitability
suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells
storage temp.
room temp
Quality Level
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Biochem/physiol Actions
General description
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How should I store a DMSO or ethanol solution of Product F3917, Forskolin?
Forskolin solutions at 5 mg/mL in either ethanol or DMSO have been found to be stable for at least 6 months at room temperature, as determined by HPLC analysis.
How can I make an aqueous solution of Product F3917, Forskolin?
Forskolin is soluble in water (with 2% ethanol) up to 0.2 mM by first dissolving in ethanol at 5 mg/mL and performing subsequent dilutions in water. Similar results were obtained with DMSO.
Will residual solvents inhibit forskolin activation of adenylate cyclase?
Various solvents, including ethanol, inhibit the forskolin activation of adenylate cyclase. DMSO is recommended for preparing forskolin solutions, because at concentrations of 5% or less of DMSO, there is little if any inhibition of forskolin activation.
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