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Fórmula empírica (notación de Hill):
C4H4O4
Número CAS:
Peso molecular:
116.07
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
207-954-9
MDL number:
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≥99%
mp
82-86 °C (lit.)
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=C1COC(=O)CO1
InChI
1S/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2
InChI key
RKDVKSZUMVYZHH-UHFFFAOYSA-N
Categorías relacionadas
General description
Glycolide is a cyclic dimer of α-hydroxy acid that can be used in the formation of aliphatic polyester. It is synthesized by the dimerization of glycolic acid. It forms a low toxic synthetic biodegradable polymer that can be used in medical applications. It is majorly used in the formation of a highly crystalline poly(glycolide) by ring opening polymerization.
Application
Glycolide can be used as a monomer in the preparation of poly(lactic-co-glycolide)(PGLA) via copolymerization with lactide monomer. PGLA is further used in the following applications:
- Porous PGLA microsphere scaffolds are used in bone repair applications.
- Encapsulated PGLA nanoparticles can be used in drug delivery and tissue engineering applications. Polymeric micro/nanoparticles made from PLGA have gained significant interest for their appealing characteristics, including biodegradability, biocompatibility, prolonged drug release, and safeguarding the drug against degradation.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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