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Merck

G8507

α-Galactosidase from green coffee beans

ammonium sulfate suspension, ≥9 units/mg protein

Sinónimos:

alpha-Galactosidase, α-D-Galactoside galactohydrolase, Melibiase

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About This Item

Número CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
Número CE:
MDL number:

Nombre del producto

α-Galactosidase from green coffee beans, ammonium sulfate suspension, ≥9 units/mg protein

form

ammonium sulfate suspension

specific activity

≥9 units/mg protein

storage temp.

2-8°C

Quality Level

Application

α-Galactosidase from green coffee beans has been used to assess the specificity of anti- α-Galactosidase antibodies. It has also been used in inhibition assay to assess N-guanidino derivatives of 1,5-dideoxy-1,5-imino-d-xylitol activity.

Biochem/physiol Actions

α-Galactosidase from green coffee beans cleaves the terminal α-galactose from the oligosaccharides. α-Galactosidase deficiency is associated with Fabry disease.

General description

α-Galactosidase from green coffee beans is encoded by the GLA gene.

Other Notes

One unit will hydrolyze 1.0 μmole of p-nitrophenyl α-D-galactoside to p-nitrophenol and D-galactose per min at pH 6.5 at 25 °C.

Physical form

Suspension in 3.2 M (NH4)2SO4 solution, pH 6.0, containing BSA

Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Eva Iniguez et al.
PLoS neglected tropical diseases, 11(10), e0006039-e0006039 (2017-10-27)
Protozoan parasites from the genus Leishmania cause broad clinical manifestations known as leishmaniases, which affect millions of people worldwide. Cutaneous leishmaniasis (CL), caused by L. major, is one the most common forms of the disease in the Old World. There
Orthoester functionalized N-guanidino derivatives of 1, 5-dideoxy-1, 5-imino-d-xylitol as pH-responsive inhibitors of beta-glucocerebrosidase
Sevvsek A, et al.
MedChemComm, 8(11), 2050-2054 (2017)
Pig xenogeneic antigen modification with green coffee bean alpha-galactosidase
Luo Y, et al.
Xenotransplantation, 6(4), 238-248 (1999)
Amblyomma sculptum tick saliva: alpha-Gal identification, antibody response and possible association with red meat allergy in Brazil
Araujo RN, et al.
International Journal For Parasitology, 46(3), 213-220 (2016)
A prophylactic alpha-Gal-based glycovaccine effectively protects against murine acute Chagas disease
Portillo S, etal.
NPJ vaccines, 4(1), 13-13 (2019)

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