H8876
5-Hydroxyindole-3-acetic acid
≥98% (HPLC), crystalline
Sinónimos:
5-HIAA
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Fórmula empírica (notación de Hill):
C10H9NO3
Número CAS:
Peso molecular:
191.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
200-195-4
MDL number:
Beilstein/REAXYS Number:
168797
Assay:
≥98% (HPLC)
Form:
crystalline
Servicio técnico
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Permítanos ayudarleNombre del producto
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline
assay
≥98% (HPLC)
form
crystalline
color
white to purple
mp
161-164 °C (dec.) (lit.)
storage temp.
−20°C
SMILES string
OC(=O)Cc1c[nH]c2ccc(O)cc12
InChI
1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)
InChI key
DUUGKQCEGZLZNO-UHFFFAOYSA-N
Gene Information
General description
5-Hydroxyindole-3-acetic acid (5-HIAA) is the catabolic end product of serotonin pathway. 5-HIAA is present in body fluids like cerebrospinal fluid (CSF), blood and urine. The expression levels of 5-HIAA is different among the normal and cancer patients. Sepiapterin reductase deficiency results in low level of 5-HIAA in CSF. 5-HIAA level is low in CSF in patients with bipolar 1 disorder with childhood attention-deficit hyperactivity disorder (ADHD).
Application
5-Hydroxyindole-3-acetic acid has been used as standard for the measurement of 5-HIAA in the brain tissue of mice using high performance liquid chromatography (HPLC).
Biochem/physiol Actions
Major serotonin metabolite.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD
Ryden E, et al.
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