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Merck

L7900

Sodium DL-lactate solution

synthetic, syrup, BioXtra, suitable for mouse embryo cell culture, 60 % (w/w)

Sinónimos:

DL-Lactic acid sodium salt

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Fórmula lineal:
CH3CH(OH)COONa
Número CAS:
Peso molecular:
112.06
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
200-772-0
Beilstein/REAXYS Number:
4332999
MDL number:
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biological source

synthetic

Quality Level

product line

BioXtra

form

syrup

concentration

60 % (w/w)

technique(s)

cell culture | embryo: suitable

storage temp.

2-8°C

SMILES string

[Na+].CC(O)C([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1

InChI key

NGSFWBMYFKHRBD-UHFFFAOYSA-M

Application

Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). This mixed isomer lactate has been qualified for use in mouse embryo culture. Lactate regulates pyruvate uptake and metabolism in the preimplantation mouse embryo.


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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M Lane et al.
Biology of reproduction, 62(1), 16-22 (1999-12-28)
This study was an investigation of the interaction of lactate on pyruvate and glucose metabolism in the early mouse embryo. Pyruvate uptake and metabolism by mouse embryos were significantly affected by increasing the lactate concentration in the culture medium. In
L J Edwards et al.
Molecular reproduction and development, 50(4), 434-442 (1998-07-21)
Although intracellular pH (pHi), is a regulator of numerous biological processes, it has received relatively little attention with regard to the physiology of the mammalian preimplantation embryo. Interestingly, there is some controversy as to whether the early embryo can recover
Marek Nalos et al.
Critical care (London, England), 18(2), R48-R48 (2014-03-29)
Acute heart failure (AHF) is characterized by inadequate cardiac output (CO), congestive symptoms, poor peripheral perfusion and end-organ dysfunction. Treatment often includes a combination of diuretics, oxygen, positive pressure ventilation, inotropes and vasodilators or vasopressors. Lactate is a marker of