L8134
Linoleic acid sodium salt
≥97% (GC)
Sinónimos:
Sodium linolate, Sodium linoleate, cis-9,cis-12-Octadecadienoic acid sodium salt
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Fórmula lineal:
C18H31O2Na
Número CAS:
Peso molecular:
302.43
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
212-491-0
MDL number:
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Permítanos ayudarleNombre del producto
Linoleic acid sodium salt, ≥97% (GC)
form
powder
InChI key
WYPBVHPKMJYUEO-NBTZWHCOSA-M
InChI
1S/C18H32O2.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20);/q;+1/p-1/b7-6-,10-9-;
SMILES string
[Na+].CCCCC\C=C/C\C=C/CCCCCCCC([O-])=O
biological source
plant oil (safflower)
assay
≥97% (GC)
technique(s)
activity assay: suitable
color
white
mp
230 °C (446 °F)
solubility
methanol: 50 mg/mL, clear, yellow
application(s)
general analytical
life science and biopharma
functional group
carboxylic acid
lipid type
omega FAs
shipped in
ambient
storage temp.
−20°C
Quality Level
Categorías relacionadas
Application
Linoleic acid sodium salt has been used:
- in the β-carotene-linoleic acid assay
- as a component in basal medium to treat peripheral blood mononuclear cells (PBMCs)
- in Dulbecco′s modified Eagle′s medium (DMEM)/F-12 HEPES (4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid) to incubate human trophoblast-derived choriocarcinoma cells (BeWo) and study its effects on adherens junctions (AJ) marker level, cell layer permeability, and intracellular lipid accumulation
Biochem/physiol Actions
Linoleic acid, as a component of acylglycosyl ceramides, plays a physiological role in maintaining the water permeability barrier of the skin. The deficiency of linoleic acid may cause poor growth or development, scaly dermatitis, and an impaired immune response in infants. It is used in cosmetic and personal care products. Linoleic acid is mainly used as emollients or moisturizers for skin, nails, and hair.
Features and Benefits
- High-quality molecule suitable for mulitple research applications
- Commonly employed in Metabolomics and Biochemical studies
General description
Linoleic acid, an essential omega-6 polyunsaturated fatty acid (PUFA), serves as a precursor to arachidonic acid (AA), necessary for synthesizing prostaglandins and other eicosanoids. Being an essential fatty acid, linoleic acid must be acquired through diet as the body cannot produce it. Deficiencies in linoleic acid are linked to health issues such as impaired wound healing, growth retardation, and dermatitis. Arachidonate 15 Lipoxygenase (15-LO) metabolizes linoleic acid in both plants and animals, forming 9- and 13-hydroxyoctadecadienoic acid (HODE). This versatile molecule finds applications in biochemical, metabolomics, and lipidomics research, enabling investigations into various metabolic pathways and providing insights into lipid functions in living organisms.
Other Notes
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