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P2795

Phytosphingosine hydrochloride

Name: Phytosphingosine hydrochloride
Brand: SIGMA

Sinónimos:

4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS

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Fórmula empírica (notación de Hill):

C₁₈H₃₉NO₃ · HCl

Número CAS:

554-62-1

Peso molecular:

353.97

NACRES:

NA.25

PubChem Substance ID:

24898363

UNSPSC Code:

12352211

MDL number:

MFCD06804643

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Propiedades

form

powder

Quality Level

200

greener alternative product score

old score: 19
new score: 9
Find out more about DOZN™ Scoring

greener alternative product characteristics

Less Hazardous Chemical Syntheses
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

, Re-engineered

lipid type

sphingolipids

storage temp.

−20°C

SMILES string

Cl.CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO

InChI

1S/C18H39NO3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20;/h16-18,20-22H,2-15,19H2,1H3;1H/t16-,17+,18-;/m0./s1

InChI key

GDKAAHDFPOWGQE-RXQQAGQTSA-N

Descripción

Biochem/physiol Actions

Phytosphingosine is a long chain sphingoid base that occurs broadly in yeast, plants and animals including mammals. In yeast it is involved in mediating the heat stress response, perhaps through activation of the AGC-type protein kinases, Pkh1, Pkh2, Ypk1, Ypk2, and Sch9. It is proapoptotic in human cancer cell lines. PHS induces ΔΨ_m and release of cytochrome c from mitochondria either directly or through activation of p38 MAPK pathway. This leads to activation of caspase 9 followed by activation of caspase 3 and programmed cell death.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number

0000524187

0000492356

0000482186

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