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Merck

P3662

Piruvato sódico

Hybri-Max, powder, suitable for hybridoma

Sinónimos:

αÁcido α-cetopropiónico sodium salt, Ácido 2-oxopropanoico sodium salt, Ácido pirúvico sodium salt

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Fórmula lineal:
CH3COCOONa
Número CAS:
Peso molecular:
110.04
UNSPSC Code:
12352205
NACRES:
NA.75
PubChem Substance ID:
EC Number:
204-024-4
Beilstein/REAXYS Number:
3568341
MDL number:
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biological source

synthetic (organic)

Quality Level

grade

Hybri-Max

assay

≥99%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

>300 °C (lit.)

solubility

H2O: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

Application

Sodium pyruvate is used by cells as an easily accessible carbohydrate source. Additionally, it is involved with amino acid metabolism and initiates the Kreb′s cycle. The 100 mM solution should be diluted 1:100 for most cell culture applications.
Sodium pyruvate has been used as a component in maturation medium for oocyte evaluation.

Biochem/physiol Actions

Sodium pyruvate is known to be an effective therapeutic target for type II citrullinaemia which is characterized by hyperammonaemia. In vivo studies proves that sodium pyruvate has protective function against hemorrhagic shock by preventing lipid peroxidation, NAD+ reduction and cleavage of poly(ADP-ribose) polymerases. Sodium pyruvate is also known to possess anti-inflammatory action and might show improvement in chronic lung disorder.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Contenido relacionado

Product Information Sheet


Treatment of a citrin-deficient patient at the early stage of adult-onset type II citrullinaemia with arginine and sodium pyruvate
Mutoh K, et al.
Journal of inherited metabolic disease, 31(2), 343-347 (2008)
Essence of Anesthesia Practice: Expert Consult-Online and Print, 685-685 (2010)
Developmental competence and mRNA expression of preimplantation in vitro-produced embryos from prepubertal and postpubertal cattle and their relationship with apoptosis after intraovarian administration of IGF-1
Zaraza J, et al.
Theriogenology, 74(1), 75-89 (2010)