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Merck

P5669

Pyridoxine

≥98%

Sinónimos:

Pyridoxol, Vitamin B6

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About This Item

Fórmula empírica (notación de Hill):
C8H11NO3
Número CAS:
Peso molecular:
169.18
NACRES:
NA.28
PubChem Substance ID:
UNSPSC Code:
12352104
EC Number:
200-603-0
MDL number:

Nombre del producto

Pyridoxine, ≥98%

InChI key

LXNHXLLTXMVWPM-UHFFFAOYSA-N

InChI

1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3

SMILES string

Cc1ncc(CO)c(CO)c1O

assay

≥98%

form

powder

technique(s)

HPLC: suitable

color

white to off-white

mp

159-162 °C (lit.)

Quality Level

Gene Information

human ... CYP1A2(1544)

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Application

Pyridoxine has been used as a component of:
  • artificial diet for sugarcane aphid pest
  • modified Strullu and Romand (MSR) medium for carrot root organ culture
  • Luria broth for E coli cultures

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.

Biochem/physiol Actions

Pyridoxine plays a key role in cell maintenance and amino acid metabolism. Deficiency of vitamin B6 leads to anemia especially in pregnant women and seizures in newborns. It serves as cofactor for heme biosynthesis during δ-amino levulinic acid formation, γ-aminobutyric acid (GABA) transaminase and glutamic acid decarboxylase. Vitamin B6 also helps in reactive oxygen species (ROS) scavenging and helps plants in overcoming the abiotic and biotic stress.

General description

Pyridoxine (vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. It is an important cofactor for metabolism.
Vitamin B group are water-soluble and exists in six forms which includes the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phospate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Vitamin B6 is distributed in nuts, whole grains and animal meat.

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Henrika Wickström et al.
AAPS PharmSciTech, 18(2), 293-302 (2016-10-16)
Printing technologies were recently introduced to the pharmaceutical field for manufacturing of drug delivery systems. Printing allows on demand manufacturing of flexible pharmaceutical doses in a personalized manner, which is critical for a successful and safe treatment of patient populations with
Design, Validation, and Application of an Enzyme-Coupled Hydrogen Sulfide Detection Assay
Lynch MJ and Crane BR
Biochemistry, 58(6), 474-483 (2018)
Pediatric Critical Care, 306(20), 2269-2269 (2011)
E B Rimm et al.
JAMA, 279(5), 359-364 (1998-02-12)
Hyperhomocysteinemia is caused by genetic and lifestyle influences, including low intakes of folate and vitamin B6. However, prospective data relating intake of these vitamins to risk of coronary heart disease (CHD) are not available. To examine intakes of folate and
Simultaneous high performance liquid chromatographic analysis of vitamins B1, B2 and B6 in royal jelly
Ana Elisa Presoto
Journal of the Brazilian Chemical Society, 15(1), 136-139 (2004)

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