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Merck

PVP360

Polyvinylpyrrolidone

powder, average molecular weight Mn 360kDa

Sinónimos:

PVP, Polyvidone, Povidone

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Fórmula lineal:
(C6H9NO)n
Número CAS:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21
MDL number:
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Nombre del producto

Polyvinylpyrrolidone, mol wt (number average molecular weight Mn 360kDa)

biological source

synthetic

Quality Level

form

powder

mol wt

(number average molecular weight Mn 360kDa)

viscosity number

80-100(lit.)

solubility

water: soluble 100 mg/mL

cation traces

heavy metals (as Pb): ≤5 ppm

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

General description

Polyvinyl pyrrolidone [poly(N-vinyl-2-pyrrolidone), PVP] is a stable, bulky, non-toxic, non-ionic polymer widely used in medical, industrial, pharmaceutical, food, cosmetic, and electronic applications. It can be prepared from N-vinyl-2-pyrrolidone by free radical polymerization.

Application

PVP can be used as:
  • A stabilizer in the synthesis of metallic nanoparticles (NPs) as it avoids the aggregation of NPs via repulsive forces produced by its hydrophobic carbon chains.
  • A capping agent in the synthesis of rodlike hydroxyapatite (HAp) nanoparticles to control the nucleation and growth of HAp crystal.
  • A synthetic polymer vehicle in the pharmaceutical industry for dispersing and suspending drugs.
  • An emulsifier and disintegrant for solution polymerization.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.


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Clase de almacenamiento

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Analía I Alet et al.
Clinical hemorheology and microcirculation, 64(2), 157-165 (2016-03-24)
Drugs used during anesthesia might induce disturbance on microcirculation due to their systemic cardiovascular actions and to direct hemorheological effects. A comparative investigation of the hemorheological alterations related to in vitro propofol treatment of red blood cells (RBCs) from healthy
Zhang Y and L Jinjun
Crystal Growth & Design, 8(7), 2101-2107 (2008)
Physicochemical Characterization of Polyvinyl Pyrrolidone: A Tale of Two Polyvinyl Pyrrolidones
Mireles LK, et al.
ACS Omega, 5(47), 30461-30467 (2020)