Saltar al contenido
Merck

RAB0275

Mouse IL-1 β ELISA Kit

for cell and tissue lysates

Sinónimos:

Cytokine detection kit

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas

Acerca de este artículo

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Il1b(16176)
Input:
sample type cell lysate
sample type tissue lysate
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle


species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell lysate
sample type tissue lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Il1b(16176)

General description

The Mouse IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1 β cell lysate and tissue lysate.

Immunogen

Recombinant Mouse IL-1 β

Application

Mouse IL-1 β ELISA Kit has been used to measure the concentration of interleukin 1 (IL)1-β in serum and bronchoalveolar lavage fluid (BALF) sample.
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Interleukin 1 β (IL-1β) stimulates the production of endogenous 92 kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). It is a proinflammatory cytokine that induces various acute and chronic inflammation. Therefore, IL-1β can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1β brings neutrophil and macrophage to the site of infection. Over expression of IL-1β in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. Mutations in IL-1β gene leads to renal manifestations and renal sequelae in Henoch-Schonlein purpura (HSP).

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


Still not finding the right product?

Explore all of our products under


Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS & Precios

  • ELISA 5X Sample Diluent Buffer (Item D2)
    SDS

  • ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
    SDS

  • 2X Cell Lysis Buffer (Item J)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Clase de almacenamiento

10 - Combustible liquids



Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos


Contenido relacionado


Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis
Heun Y, et al.
EBioMedicine (2019)
Protective effects of fucoidan against hyperoxic lung injury via the ERK signaling pathway
Nie M, et al.
Molecular Medicine Reports, 17(1), 1813-1818 (2018)
Strain- and host species-specific inflammasome activation, IL-1? release, and cell death in macrophages infected with uropathogenic Escherichia coli.
Schaale K
Mucosal Immunology, 9(1), 124-136 (2016)