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Fórmula empírica (notación de Hill):
C15H11I3NNaO4
Número CAS:
Peso molecular:
672.96
UNSPSC Code:
51111800
NACRES:
NA.32
PubChem Substance ID:
EC Number:
200-223-5
Beilstein/REAXYS Number:
8179867
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥95% (HPLC)
Servicio técnico
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Permítanos ayudarlebiological source
synthetic (organic)
Quality Level
assay
≥95% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
ethanol/1 M HCl (4:1): 10 mg/mL, clear, colorless to faintly yellow or pink
shipped in
ambient
storage temp.
−20°C
SMILES string
[Na+].N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C([O-])=O
InChI
1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
InChI key
SBXXSUDPJJJJLC-YDALLXLXSA-M
Gene Information
human ... THRA(7067), THRB(7068)
rat ... Thra(81812), Thrb(24831)
Application
3,3′,5-Triiodo-L-thyronine sodium salt was used in Oligodendrocyte differentiation medium used for isolation and culture of rat and mouse oligodendrocyte precursor cells. The product was used as a test compound for incubating adipocyte cells, used for studying the impact of hormones and butyrate on modulation of porcine adipocyte beta-adrenergic receptors.
Biochem/physiol Actions
3,3′,5-Triiodo-L-thyronine also referred to as O-(4-Hydroxy-3-iodophenyl)−3,5−diiodo-L-tyrosine sodium salt or T3 is the biologically active thyroid hormone. In hypothyroidism pateints, triiodothyronine can enhance mood and neuropsychological function. The product also positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation.
Preparation Note
3,3′,5-Triiodo-L-thyronine sodium salt dissolves in 1 M HCl:EtOH with a ratio of 1:4 at 10 mg/ml to yield a clear, colorless to yellow or faint pink solution.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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