00922
Difluoroacetic acid
for LC-MS LiChropur™, ≥97.5% (GC)
Sinónimos:
DFA
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Fórmula lineal:
F2CHCO2H
Número CAS:
Peso molecular:
96.03
UNSPSC Code:
41116004
NACRES:
NB.21
MDL number:
Beilstein/REAXYS Number:
1098588
Servicio técnico
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Permítanos ayudarleQuality Level
assay
≥97.5% (GC), 97.5-102.5% (T)
technique(s)
LC/MS: suitable
refractive index
n20/D 1.344 (lit.)
bp
132-134 °C (lit.)
mp
−1 °C (lit.)
density
1.526 g/mL at 25 °C (lit.)
cation traces
Al: ≤5 ppm, Ca: ≤20 ppm, Cu: ≤5 ppm, Fe: ≤2 ppm, K: ≤50 ppm, Mg: ≤5 ppm, Na: ≤50 ppm
suitability
passes test for LC-MS
SMILES string
OC(=O)C(F)F
InChI
1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)
InChI key
PBWZKZYHONABLN-UHFFFAOYSA-N
General description
Compared to trifluoroacetic acid (TFA), difluoroacetic acid (DFA) exhibits an improved sensitivity in mass spectral detection (ESI) as it has a reduced effect on ion suppression in reversed-phase liquid chromatography (RPLC-MS), while keeping its strong chromatographic performance enhancing effects.
Difluoroaceticacid is used in liquid chromatography-mass spectrometry applications. It is a volatile, low molecular-weight organic acid that improves the ionization and resolution of many molecules.
Difluoroaceticacid is used in liquid chromatography-mass spectrometry applications. It is a volatile, low molecular-weight organic acid that improves the ionization and resolution of many molecules.
Application
Difluoroacetic acid can be used as an:
- Acidifier in liquid chromatography (LC) experiments.
- Ion-pairing agent in the HILIC-MS (hydrophilic interaction liquid chromatography-mass spectrometry) analysis of intact pharmaceutical glycoproteins.
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Clase de almacenamiento
8A - Combustible corrosive hazardous materials
flash_point_f
172.4 °F - closed cup
flash_point_c
78 °C - closed cup
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