Skip to Content
Merck

24370C

EX-CELL® Advanced HD Perfusion Medium

powder

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

UNSPSC Code:
12352200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Level

product line

EX-CELL®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

shipped in

ambient

storage temp.

2-8°C

General description

EX-CELL® Advanced HD Perfusion Medium is chemically-defined and contains no animal derived components. The new medium has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in perfusion cultures while still allowing for flexibility in the adjustment of protein quality attributes. This medium was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, protein expression and glycosylation. This medium is intended to be used in perfusion processes. While the medium was developed specifically for steady-state perfusion, it can also support other perfusion applications such as N-1, continuous fed-batch and production perfusion where cells are not bled.

Preparation Note

Formulated to contain 28.57 grams of powder per liter of medium.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3



Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.


Articles

Streamline upstream process monitoring with embedded Raman ready-to-use models for easy implementation and improved process understanding

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

View All Articles

Related Content

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Biopharmaceutical developers need efficient, productive upstream processes that deliver high quality monoclonal antibodies (mAbs) and other types of recombinant proteins. Process intensification can future-proof their manufacturing strategies, reduce costs, and increase facility flexibility.

生物制药开发商需要高效、高产的上游工艺,以生产高质量的单克隆抗体(mAbs)及其他类型的重组蛋白。工艺强化能够使他们的生产策略具备前瞻性,降低成本,并提高生产设施的灵活性。

View All Related Content