D0676
Dobutamine hydrochloride
≥98% (TLC), powder, α1, β1 and β2-adrenoceptor agonist
Synonym(s):
(±)-3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-β-phenethylamine hydrochloride
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About This Item
Product Name
Dobutamine hydrochloride, ≥98%
Quality Level
assay
≥98%
form
powder
originator
Eli Lilly
storage temp.
2-8°C
SMILES string
Cl[H].CC(CCc1ccc(O)cc1)NCCc2ccc(O)c(O)c2
InChI
1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H
InChI key
BQKADKWNRWCIJL-UHFFFAOYSA-N
Gene Information
human ... ADRB1(153), ADRB2(154)
Application
- to treat mouse embryonic fibroblasts for cell death analysis
- to inhibit TAZ (transcriptional coactivator with PDZ-binding motif)/YAP (Yes-associated protein) of Hippo pathway and study its effect on tumor cell proliferation
- as β1-AR partial agonist to determine its effects on budding of endophilin-mRFP-positive structures by live-cell imaging
Biochem/physiol Actions
Features and Benefits
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Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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