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Merck

Y0001285

Sertraline impurity E

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

(R)-(−)-Mandelic acid, (R)-α-Hydroxyphenylacetic acid

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Acerca de este artículo

Fórmula lineal:
C6H5CH(OH)CO2H
Número CAS:
Peso molecular:
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2691094
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Nombre del producto

Sertraline impurity E, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)/t7-/m1/s1

SMILES string

O[C@@H](C(O)=O)c1ccccc1

InChI key

IWYDHOAUDWTVEP-SSDOTTSWSA-N

grade

pharmaceutical primary standard

API family

sertraline

manufacturer/tradename

EDQM

mp

131-133 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Sertraline impurity E EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Tsuyoshi Mita et al.
The Journal of organic chemistry, 77(5), 2159-2168 (2012-02-01)
Incorporation reactions of carbon dioxide (CO(2)) with N-Boc-α-amido and α-acetoxy stannanes were developed using CsF as a mild tin activator. Monoprotected α-amido stannanes could be used, and the corresponding arylglycine derivatives were obtained in moderate-to-high yields under 1 MPa (10
Shimin Mao et al.
Journal of separation science, 35(17), 2273-2281 (2012-07-19)
Resolution of racemic mandelic acid ((R,S)-MA) and numerical determination of binary competitive isotherm of (R,S)-MA on Chiralcel-OD column have been investigated in this study. The effects of the alcohol modifier and acidic additive in the mobile phase on the retention
Benedict T Green et al.
The Journal of pharmacology and experimental therapeutics, 344(1), 295-307 (2012-10-23)
Coniine is an optically active toxic piperidine alkaloid and nicotinic acetylcholine receptor (nAChR) agonist found in poison hemlock (Conium maculatum L.). Coniine teratogenicity is hypothesized to be attributable to the binding, activation, and prolonged desensitization of fetal muscle-type nAChR, which
Selahattin Bozkurt et al.
Chirality, 24(2), 129-136 (2011-12-20)
Novel chiral calix[4]arene derivatives bearing amino alcohol moieties at the lower rim have been synthesized from the reaction of p-tert-butylcalix[4]arene diester with various amino alcohols. The transport of amino acid esters (phenylglycine, phenylalanine, and tryptophan methyl esters hydrochloride) and mandelic

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