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A6636

Aflatoxin B₁

greener alternative

from Aspergillus flavus, ≥98.0% (HPLC), powder, CYP1A2, CYP2A6, CYP2D6, and CYP3A family substrate

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Fórmula empírica (notación de Hill):
C17H12O6
Número CAS:
1162-65-8
Peso molecular:
312.27
NACRES:
NA.77
PubChem Substance ID:
24891116
UNSPSC Code:
12352200
EC Number:
214-603-3
MDL number:
MFCD00869647
Beilstein/REAXYS Number:
1269174
Assay:
≥98.0% (HPLC)
Form:
powder
Quality level:
300
Servicio técnico
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Nombre del producto

Aflatoxin B1 from Aspergillus flavus, from Aspergillus flavus

biological source

Aspergillus flavus

Quality Level

300

assay

≥98.0% (HPLC)

form

powder

greener alternative product score

old score: 51
new score: 42
Find out more about DOZN™ Scoring

greener alternative product characteristics

Waste Prevention
Designing Safer Chemicals
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

Re-engineered,

storage temp.

2-8°C

SMILES string

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCC5=O)c14

InChI

1S/C17H12O6/c1-20-10-6-11-14(8-4-5-21-17(8)22-11)15-13(10)7-2-3-9(18)12(7)16(19)23-15/h4-6,8,17H,2-3H2,1H3/t8-,17+/m0/s1

InChI key

OQIQSTLJSLGHID-WNWIJWBNSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Designing Safer Chemicals” and “Design for Energy Efficiency”. Click here to view its DOZN scorecard.

Application

Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. Aflatoxin B1 may be used as an internal standard when testing for aflatoxin contamination in food products.

Biochem/physiol Actions

Aflatoxin B1 is a carcinogenic compound produced by Aspergillus flavus, a common soil fungus, that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene. Aflatoxin B1 is a food contaminant and a hepatocarcinogen. Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation. Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR). Aflatoxin B1 is a CYP1A2, CYP2A6, CYP2D6, and CYP3A family substrate.

Disclaimer

Possibly carcinogenic.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Carc. 1B - Muta. 1B

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
0000486553
0000486553
0000477743
0000477743
0000460656

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