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C4024

Carbamazepine

Name: Carbamazepine
Brand: SIGMA

≥98% (HPLC), powder, sodium channel inhibitor

Sinónimos:

5H-Dibenz[b,f]azepine-5-carboxamide

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Fórmula empírica (notación de Hill):

C₁₅H₁₂N₂O

Número CAS:

298-46-4

Peso molecular:

236.27

UNSPSC Code:

12352200

eCl@ss:

34051404

PubChem Substance ID:

57654002

NACRES:

NA.77

EC Number:

206-062-7

MDL number:

MFCD00005073

Form:

powder

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Propiedades

Nombre del producto

Carbamazepine, powder

form

powder

Quality Segment

100

mp

191-192 °C (lit.)

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL, H₂O: insoluble, ethanol: soluble, propylene glycol: soluble

originator

Novartis

storage temp.

2-8°C

SMILES string

NC(=O)N1c2ccccc2C=Cc3ccccc13

InChI

1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

InChI key

FFGPTBGBLSHEPO-UHFFFAOYSA-N

Gene Information

Descripción

Application

Carbamazepine has been used to investigate its behavior in wastewater treatment and during groundwater infiltration. It has also been used to find out its effects on spontaneous seizures in rats.

Biochem/physiol Actions

Carbamazepine is considered as a safe antiepileptic drug. It decreases the multiple drug therapy and maintains a better control of epilepsy.

Anticonvulsant; ligand for the GABA_A receptor benzodiazepine modulatory site. Sodium channel inhibitor.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Pictogramas

GHS08,GHS07

Palabra de advertencia

Danger

Códigos de peligro

H302,H317,H334,H336,H360FD

Indicaciones de precaución

P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3

Órganos diana

Central nervous system

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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WGK 2

Punto de inflamación (°F)

Not applicable

Punto de inflamación (°C)