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344350 Foxm1b Inhibitor, Cell-permeable

Foxm1b Inhibitor, Cell-permeable MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: RRRRRRRRR-KFVRSRRPRTASCALAFVN, (D-Arg)₉-p19ARF26-44

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Overview

Replacement Information
Description
OverviewA cell-permeable p19ARF26-44 tumor suppressor peptide that contains an N-terminal membrane transducing nine D-Arginine sequence and inhibits the transcriptional activity of Foxm1b (Forkhead Box m1b). Shown to significantly diminish growth of Foxm1b-transfected U2OS cells, while exhibiting no cytotoxic or apoptotic effects towards non-transfected cells at the same peptide concentration (12 µM).
Catalogue Number344350
Brand Family Calbiochem®
SynonymsRRRRRRRRR-KFVRSRRPRTASCALAFVN, (D-Arg)₉-p19ARF26-44
References
ReferencesKalinichenko, V.V., et al. 2004. Genes Dev. 18, 830.
Product Information
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₄₉H₂₆₇N₆₉O₃₃S
Chemical formulaC₁₄₉H₂₆₇N₆₉O₃₃S
Hygroscopic Hygroscopic
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide SequenceH-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Lys-Phe-Val-Arg-Ser-Arg-Arg-Pro-Arg-Thr-Ala-Ser-Cys-Ala-Leu-Ala-Phe-Val-Asn-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution in degassed H₂O, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Unstable in buffer.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
344350 0

Documentation

Foxm1b Inhibitor, Cell-permeable Certificates of Analysis

TitleLot Number
344350

References

Reference overview
Kalinichenko, V.V., et al. 2004. Genes Dev. 18, 830.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-June-2008 RFH
SynonymsRRRRRRRRR-KFVRSRRPRTASCALAFVN, (D-Arg)₉-p19ARF26-44
DescriptionA cell-permeable p19ARF26-44 tumor suppressor peptide that contains an N-terminal, membrane transducing nine D-Arginine sequence and inhibits the transcriptional activity of Forkhead Box m1b (Foxm1b). Shown to significantly diminish growth of Foxm1b-transfected U2OS cells, while exhibiting no cytotoxic or apoptotic effects in non-transfected cells at the same peptide concentration (12 µM).
FormWhite lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₄₉H₂₆₇N₆₉O₃₃S
Peptide SequenceH-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-Lys-Phe-Val-Arg-Ser-Arg-Arg-Pro-Arg-Thr-Ala-Ser-Cys-Ala-Leu-Ala-Phe-Val-Asn-OH
Purity≥95% by HPLC
SolubilityDegassed H₂O (1 mg/ml)
Storage Protect from light
-20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution in degassed H₂O, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C. Unstable in buffer.
Toxicity Standard Handling
ReferencesKalinichenko, V.V., et al. 2004. Genes Dev. 18, 830.