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Merck

PHR1050

Acide benzoïque

Pharmaceutical Secondary Standard; Certified Reference Material

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A propos de cet article

Formule linéaire :
C6H5COOH
Numéro CAS:
65-85-0
Poids moléculaire :
122.12
NACRES:
NA.24
PubChem Substance ID:
329823080
eCl@ss:
39023903
UNSPSC Code:
41116107
EC Number:
200-618-2
MDL number:
MFCD00002398
Beilstein/REAXYS Number:
636131

Principaux documents

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Nom du produit

Acide benzoïque, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

WPYMKLBDIGXBTP-UHFFFAOYSA-N

InChI

1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)

SMILES string

OC(=O)c1ccccc1

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1055002

vapor density

4.21 (vs air)

vapor pressure

10 mmHg ( 132 °C)

description

API family: benfluorex

API family

metronidazole, benfluorex, mefenamic acid

CofA

current certificate can be downloaded

autoignition temp.

1061 °F

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

249 °C (lit.)

mp

121-125 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Catégories apparentées

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Application

Benzoic acid may be used as a reference standard in determining the concentration of benzoic acid in food and milk samples using high performance liquid chromatography coupled with photodiode array detector (HPLC).

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB8257 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Health hazardCorrosion
GHS08,GHS05

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation

target_organs

Lungs

Classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Determination of benzoic and sorbic acids in Brazilian food
Qi P, et al.
Food Control, 20, 414-418 (2009)
Determination of benzoic and sorbic acids in Brazilian food
Tfouni.V.A.S and Toledo F.C.M
Food Control, 13, 117-123 (2002)
S Nacht et al.
Journal of the American Academy of Dermatology, 4(1), 31-37 (1981-01-01)
The transepidermal penetration and metabolic disposition of 14C-benzoyl peroxide were assessed in vitro (excised human skin) and in vivo (rhesus monkey). In vitro, the benzoyl peroxide penetrated into the skin, through the stratum corneum or the follicular openings, or both
Ly Dieu Tran et al.
Journal of the American Chemical Society, 134(44), 18237-18240 (2012-10-30)
An auxiliary-assisted, copper catalyzed or promoted sulfenylation of benzoic acid derivative β-C-H bonds and benzylamine derivative γ-C-H bonds has been developed. The method employs disulfide reagents, copper(II) acetate, and DMSO solvent at 90-130 °C. Application of this methodology to the
Wanchun Xiang et al.
ChemSusChem, 6(2), 256-260 (2013-01-25)
Sensing the sun: Incorporation of a cyanomethyl benzoic acid electron acceptor into donor-π-acceptor sensitizers for dye-sensitized-solar cell is shown to lead to devices with improved conversion efficiency when compared with more widely used cyanoacetic acid acceptor.
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