E6530
エトミデート
>98% (HPLC), GABAA potentiator, powder
別名:
R16659, アミデート
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この商品について
実験式（ヒル表記法）:
C14H16N2O2
CAS番号:
分子量:
244.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
251-385-9
MDL number:
Assay:
>98% (HPLC)
Form:
powder
製品名
エトミデート, >98% (HPLC), powder
Quality Segment
assay
>98% (HPLC)
form
powder
color
white
solubility
DMSO: >10 mg/mL
originator
Johnson & Johnson
storage temp.
2-8°C
SMILES string
CCOC(=O)c1cncn1[C@H](C)c2ccccc2
InChI
1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
InChI key
NPUKDXXFDDZOKR-LLVKDONJSA-N
Gene Information
General description
Etomidate is an imidazole derivative, which functions as an nonbarbiturate hypnotic agent. It is used in speech and memory test. Etomidate regulates hemodynamic stability by preserving sympathetic outflow and autonomic reflexes. It inhibits adrenal steroidogenesis.
Biochem/physiol Actions
エトミデ-トは全身麻酔薬であり、GABAA伝達を増強します。ストレプトゾトシン (STZ) 誘発性高血糖に対するエトミデ-トの神経保護作用について、ラットの脳、脊髄を用いて検討されました。エトミデ-ト投与により糖尿病性酸化的損傷に対する神経組織保護の効果が示されました。
Etomidate is a general anesthetic; potentiates GABAA transmission
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves