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Merck

COL1A1

collagen, type I, alpha 1

Synonymes:
OI4
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1277) Summary: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12842) collagen, type I, alpha 1
  • Rat(29393) collagen, type I, alpha 1
  • domestic guinea pig(100733209) collagen, type I, alpha 1
  • chicken(395532) collagen, type I, alpha 1
  • domestic cat(101092216) collagen, type I, alpha 1
  • dog(403651) collagen, type I, alpha 1
  • sheep(443483) collagen, type I, alpha 1
  • Goat(100860828) collagen, type I, alpha 1
  • cow(282187) collagen, type I, alpha 1
  • Horse(100033877) collagen, type I, alpha 1
  • Domestic Rabbit(100008952) collagen, type I, alpha 1
  • naked mole-rat(101703193) collagen, type I, alpha 1

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anticorps monoclonal anti-collagène de type I antibody produced in mouse, clone COL-1, ascites fluid,
Espèces réactives
bovine, deer, human, pig, rabbit, rat
Application
ELISA
dot blot

immunohistochemistry
Anti-Collagen Type I antibody, Mouse monoclonal, clone COL-1, purified from hybridoma cell culture,
Espèces réactives
bovine, deer, human, pig, rat
Application
ELISA
dot blot

immunohistochemistry

western blot
Anticorps anti-collagène de souris de type I, Chemicon®, from rabbit,
Espèces réactives
mouse
Application
ELISA
immunohistochemistry

radioimmunoassay

western blot
Anti-Procollagen Type I Antibody, NT, clone M-58, culture supernatant, clone M-58, Chemicon®,
Espèces réactives
human
Application
immunohistochemistry
Anticorps anti-collagène de type I, Chemicon®, from goat,
Espèces réactives
bovine, human
Application
ELISA
dot blot

immunocytochemistry

immunohistochemistry

western blot

Proteins

Numéro du produit
Description
Espèce(s)
Collagène de type I solution from rat tail, BioReagent, suitable for cell culture, sterile-filtered,
Espèce(s)
rat
Collagène de type I, queue de rat, 100 mg, solution, BioReagent, suitable for cell culture,
Espèce(s)
rat
Collagen from calf skin, Bornstein and Traub Type I, solid, BioReagent, suitable for cell culture,
Espèce(s)
cow
Collagène from rat tail, Bornstein and Traub Type I, powder, BioReagent, suitable for cell culture,
Espèce(s)
rat
Rat Tail Collagen Coating Solution (20 ML), Type I, 50 μg/mL, solution, BioReagent, suitable for cell culture,
Espèce(s)
rat

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human COL1A1,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Col1a1,
Espèce(s)
mouse