198978
3-Methyl-2-oxopentanoic acid sodium salt
≥98%
Synonyme(s) :
2-Keto-3-methylvaleric acid sodium salt, 3-Methyl-2-oxopentanoic acid sodium salt, Ketoisoleucine sodium salt
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A propos de cet article
Formule linéaire :
C2H5CH(CH3)COCO2Na
Numéro CAS:
Poids moléculaire :
152.12
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
266-503-4
MDL number:
Assay:
≥98%
Form:
powder
Service technique
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Laissez-nous vous aiderQuality Level
assay
≥98%
form
powder
mp
204-206 °C (lit.)
functional group
ketone
SMILES string
[Na+].CCC(C)C(=O)C([O-])=O
InChI
1S/C6H10O3.Na/c1-3-4(2)5(7)6(8)9;/h4H,3H2,1-2H3,(H,8,9);/q;+1/p-1
InChI key
SMDJDLCNOXJGKC-UHFFFAOYSA-M
Application
3-Methyl-2-oxopentanoic acid sodium salt may be used in chemical synthesis studies.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Analysis of (S)- and (R)-3-methyl-2-oxopentanoate enantiomorphs in body fluids.
P Schadewaldt
Methods in enzymology, 324, 33-39 (2000-09-16)
Hsueh-Meei Huang et al.
Biochimica et biophysica acta, 1637(1), 119-126 (2003-01-16)
Mitochondrial dysfunction occurs in many neurodegenerative diseases. The alpha-ketoglutarate dehydrogenase complex (KGDHC) catalyzes a key and arguably rate-limiting step of the tricarboxylic acid cycle (TCA). A reduction in the activity of the KGDHC occurs in brains and cells of patients
D E Ward et al.
Journal of bacteriology, 182(11), 3239-3246 (2000-05-16)
Recently the bkd gene cluster from Enterococcus faecalis was sequenced, and it was shown that the gene products constitute a pathway for the catabolism of branched-chain alpha-keto acids. We have now investigated the regulation and physiological role of this pathway.