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Merck

234907

2-(Dimethylamino)ethyl methacrylate

contains 700-1000 ppm monomethyl ether hydroquinone as inhibitor, 98%

Synonyme(s) :

Methacrylic acid 2-(dimethylamino)ethyl ester

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A propos de cet article

Formule linéaire :
CH2=C(CH3)COOCH2CH2N(CH3)2
Numéro CAS:
Poids moléculaire :
157.21
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1757048
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Nom du produit

2-(Dimethylamino)ethyl methacrylate, contains 700-1000 ppm monomethyl ether hydroquinone as inhibitor, 98%

InChI

1S/C8H15NO2/c1-7(2)8(10)11-6-5-9(3)4/h1,5-6H2,2-4H3

SMILES string

CN(C)CCOC(=O)C(C)=C

InChI key

JKNCOURZONDCGV-UHFFFAOYSA-N

vapor density

5.4 (vs air)

vapor pressure

<1 mmHg ( 25 °C)

assay

98%

form

liquid

contains

700-1000 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.439 (lit.)

bp

182-192 °C (lit.)

density

0.933 g/mL at 25 °C (lit.)

storage temp.

2-8°C

Quality Level

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Application

2-(Dimethylamino)ethyl methacrylate (DMAEMA) can be used as starting material in the synthesis of poly (DMAEMA) and amphiphilic block copolymers. Poly (DMAEMA) is a thermal and pH-sensitive biocompatible polymer widely used in the following applications.

  • Quaternized poly (DMAEMA) can be used to prepare highly efficient antibacterial magnetic particles. The high density of quaternary ammonium groups generated via surface-initiated ATRP are responsible for high antibacterial activity.
  • Ag nanoparticles immobilized into a poly (DMAEMA) brush layer can be used as a sensor platform for the detection of organic molecules by surface-enhanced Raman spectroscopy (SERS).
  • It can also be used to prepare stable polymer-based gene delivery systems.

General description

2-(Dimethylamino)ethyl methacrylate (DMAEMA) is a methacrylic acid derivative that is used as a monomer in the production of polymers with a wide range of applications. The most common use of DMAEMA is in the production of cationic polymers, which are highly charged and have applications such as flocculants, coagulants, dispersants, and stabilizers. In addition, DMAEMA-based polymers have found uses in drug delivery systems, tissue engineering, and gene therapy, owing to their excellent biocompatibility and biodegradability properties. DMAEMA can also be used as a modifying agent in coatings, adhesives, and textiles to improve properties such as adhesion, hardness, and water resistance.

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Consulter la Bibliothèque de documents

Miao Wang et al.
Colloids and surfaces. B, Biointerfaces, 103, 52-58 (2012-12-04)
Grafting-from has proven to be a very effective way to create high grafting densities and well-controlled polymer chains on different kinds of surfaces. In this work, we aim to graft zwitterionic brush from cellulose membrane (CM) via ARGET-ATRP (Activator Regenerated
Bogna Stawarczyk et al.
The Journal of prosthetic dentistry, 106(6), 386-398 (2011-12-03)
Flexural strength, hardness, surface roughness, discoloration, and abrasion resistance are important properties of veneering composite resins. Recently introduced veneering resins are purported to have enhanced mechanical properties due to their composition, but their long-term durability is not known. The purpose
Anu M Alhoranta et al.
Biomacromolecules, 12(9), 3213-3222 (2011-07-19)
A series of amphiphilic star and linear block copolymers were synthesized using ATRP. The core consisted of either polystyrene (PS) or poly(n-butyl acrylate) (PBuA), having different glass-transition (T(g)) values. These polymers were used as macroinitiators in the polymerization of the
Saadyah E Averick et al.
Biomacromolecules, 13(11), 3445-3449 (2012-09-13)
Cationic nanogels with site-selected functionality were designed for the delivery of nucleic acid payloads targeting numerous therapeutic applications. Functional cationic nanogels containing quaternized 2-(dimethylamino)ethyl methacrylate and a cross-linker with reducible disulfide moieties (qNG) were prepared by activators generated by electron
Freeze-drying of poly((2-dimethylamino)ethyl methacrylate)-based gene delivery systems.
J Y Cherng et al.
Pharmaceutical research, 14(12), 1838-1841 (1998-02-07)

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