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Merck

364959

N-[Tris(hydroxymethyl)methyl]acrylamide

contains ≤7% KCl, 93%

Synonyme(s) :

NAT, TRIS-acrylamide

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A propos de cet article

Formule linéaire :
H2C=CHCONHC(CH2OH)3
Numéro CAS:
Poids moléculaire :
175.18
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
237-645-4
Beilstein/REAXYS Number:
2081162
MDL number:
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Quality Level

assay

93%

form

solid

contains

≤7% KCl

mp

136-141 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(CO)(CO)NC(=O)C=C

InChI

1S/C7H13NO4/c1-2-6(12)8-7(3-9,4-10)5-11/h2,9-11H,1,3-5H2,(H,8,12)

InChI key

MVBJSQCJPSRKSW-UHFFFAOYSA-N

Application


  • Reactions of dipropilamine with unsaturated surfactants in the model oil–water system: This study investigates the reactions of dipropilamine with N-[tris(hydroxymethyl)methyl]acrylamide, highlighting potential applications in industrial and pharmaceutical processes (Simonian, 2015).

  • Water-dispersible polymer coated silica nanoparticle for turn-on fluorometric detection of Cephalexin: Utilizes N-[Tris(hydroxymethyl)methyl]acrylamide in the synthesis of a polymer to improve the detection capabilities for pharmaceutical applications, showcasing the adaptability of this monomer in enhancing sensor technologies (Sahu et al., 2022).

  • Ultrasound-triggered piezocatalytic composite hydrogels for promoting bacterial-infected wound healing: Features a hydrogel based on N-[tris(hydroxymethyl)methyl]acrylamide for medical applications, particularly in accelerating wound healing, which is crucial for drug delivery systems and tissue engineering (Liu et al., 2023).

  • An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation: Describes the development of a hydrogel incorporating N-[tris(hydroxymethyl)methyl]acrylamide for potential medical use in treating internal wounds, demonstrating the material′s medical applications in a clinical setting (Webb et al., 2022).


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Fabian Leinisch et al.
Free radical biology & medicine, 112, 240-252 (2017-08-02)
Protein oxidation is a frequent event as a result of the high abundance of proteins in biological samples and the multiple processes that generate oxidants. The reactions that occur are complex and poorly understood, but can generate major structural and
Yasmin Spahr et al.
Open forum infectious diseases, 5(5), ofy077-ofy077 (2018-05-22)
Paramyxoviruses include respiratory syncytial virus (RSV), parainfluenza virus (PIV), and human metapneumovirus (MPV), which may cause significant respiratory tract infectious disease (RTID) and mortality after allogeneic hematopoietic cell transplantation (HCT). However, clinical data regarding frequency and outcome are scarce. We
M Kozulić et al.
Analytical biochemistry, 163(2), 506-512 (1987-06-01)
We describe in detail the synthesis of an acrylic monomer, N-acryloyl-tris(hydroxy-methyl)aminomethane (NAT), which was successfully used for the preparation of gels for electrophoresis and isoelectric focusing. The polymerization kinetics and transparency of the poly(NAT) gels crosslinked by N,N'-methylenebisacrylamide (Bis) are