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Merck

376914

Poly(methyl methacrylate-co-methacrylic acid)

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

Synonyme(s) :

Poly(methacrylic acid-co-methyl methacrylate)

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A propos de cet article

Numéro CAS:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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SMILES string

O(C)C(=O)C(=C)C.OC(=O)C(=C)C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

InChI key

IWVKTOUOPHGZRX-UHFFFAOYSA-N

feed ratio

1:0.016 (methyl methacrylate:methacrylic acid)

mol wt

average Mn ~15,000 by GPC, average Mw ~34,000 by GPC

inherent viscosity

0.19 dL/g(lit.)

transition temp

Tg 105 °C

Application

  • Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Loaded with Aspirin: This study focuses on the preparation and potential therapeutic applications of biocompatible nanoparticles loaded with aspirin, highlighting their suitability for medical use (López-Muñoz et al., 2019).
  • Biocompatible and biodegradable ultrafine nanoparticles of poly (methyl methacrylate-co-methacrylic acid) prepared via semicontinuous heterophase: Discusses the synthesis of biodegradable nanoparticles for potential biomedical applications, emphasizing their eco-friendly nature and suitability for drug delivery systems (Saade et al., 2016).
  • Synthesis and characteristics of poly(methyl methacrylate‐co‐methacrylic acid)/poly(methacrylic acid‐co‐N‐isopropylacrylamide) thermosensitive semi‐hollow latex: Explores the unique properties of thermosensitive latex particles for advanced material applications, potentially useful in smart drug delivery systems (Lee et al., 2014).
  • Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin: Examines the use of polymeric nanofibers for controlled drug release, particularly for cancer treatment, demonstrating the versatility of poly(methyl methacrylate-co-methacrylic acid) in pharmaceutical applications (López-Muñoz et al., 2023).

Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Suprita A Tawde et al.
Vaccine, 30(38), 5675-5681 (2012-07-04)
Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US. Customized immunotherapeutic strategies may serve as an alternative method to control the recurrence or progression of ovarian cancer and to avoid severe adverse
Yan Zhang et al.
International journal of pharmaceutics, 436(1-2), 341-350 (2012-07-07)
In the present study thiolated Eudragit L100 (Eul) based polymeric nanoparticles (NPs) were employed to develop an oral insulin delivery system. Sulfydryl modification was achieved by grafting cysteine to the carboxylic acid group of Eudragit L100, which displayed maximum conjugate
Martins Emeje et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 71-82 (2012-04-05)
Sustained release (SR) dosage forms enable prolonged and continuous deposition of the drug in the gastrointestinal (GI) tract and improve the bioavailability of medications characterized by a narrow absorption window. In this study, a new strategy is proposed for the
Katia P Seremeta et al.
Colloids and surfaces. B, Biointerfaces, 102, 441-449 (2012-09-27)
The design of simple and scalable drug delivery systems to target the central nervous system (CNS) could represent a breakthrough in the addressment of the HIV-associated neuropathogenesis. The intranasal (i.n.) route represents a minimally invasive strategy to surpass the blood-brain
Huasheng Yang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1427-1430 (2012-07-12)
Using Apocynum venetum as a model drug to prepare pulsed-release tablets based on diffusion, swelling, osmotic pressure mechanism and to evaluate the release characteristics. The pulsatile release tablets were prepared by film coating methods using HPMC E5 and Eudragit The

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