675075
8-Mercaptooctanoic acid
95%
Synonyme(s) :
8-Thiooctanoic acid, MOA
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A propos de cet article
Formule empirique (notation de Hill) :
C8H16O2S
Numéro CAS:
Poids moléculaire :
176.28
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
Service technique
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Laissez-nous vous aiderQuality Level
assay
95%
refractive index
n20/D 1.4808
density
1.0326 g/mL at 25 °C
storage temp.
−20°C
SMILES string
OC(=O)CCCCCCCS
InChI
1S/C8H16O2S/c9-8(10)6-4-2-1-3-5-7-11/h11H,1-7H2,(H,9,10)
InChI key
FYEMIKRWWMYBFG-UHFFFAOYSA-N
General description
8-mercaptooctanoic acid (MOA) forms a self-assembled monolayer (SAM) on the surface of nanoparticles. MOA consists of thiol and carboxylic groups which helps in the surface treatment of different nanoparticles.
8-Mercaptooctanoic acid (MOA) is an carboxylic acid terminated alkanethiol that forms self-assembled monolayers (SAMs) that facilitate subsequent surface immobilization of other molecular species.
Application
MOA is a used as a SAM for surface modification of gold electrodes for quartz crystal microbalance (QCMB) measurement. It may be used as a monolayer that facilitates ferritin absorption on gold electrodes for uptake of excess iron in the cell. It may also be used for preparation of nitric oxide based gold nanoparticles (NO-AuNPs) for macrophage photo-thermal therapy under NIR irradiation.
MOA may form SAM that can be used in the surface modification of gold electrodes which are useful for the study of surface characteristics of ferritin. It may also be used to form SAM with hydrophilic end groups to be used as a protective coating on the electrodes for efficient electron transport in semiconductor devices.
This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with carboxylic acids can be further functionalized to introduce more complex end groups. Can also be used to form a protective barrier monolayer to allow deposition of a passivating oxide layer.
Other Notes
This product should be stored in the freezer, 0 to -20 °C
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Contenu apparenté
Linan Liu et al.
EBioMedicine, 47, 563-577 (2019-09-11)
This study aims to evaluate the quality of preclinical data, determine the effect sizes, and identify experimental measures that inform efficacy using mesenchymal stromal (or stem) cells (MSC) therapy in animal models of rheumatoid arthritis (RA). Literature searches were performed
Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages.
Park J, et al.
Chemical Communications (Cambridge, England), 53(81), 11229-11232 (2017)
Anna Paula V Moura et al.
ACS central science, 3(9), 1026-1031 (2017-10-06)
Secreted and surface-displayed carbohydrates are essential for virulence and viability of many parasites, including for immune system evasion. We have identified the α-Gal trisaccharide epitope on the surface of the protozoan parasites