678937
Tris[(1-benzyl-1H-1, 2, 3-triazol-4-yl)methyl]amine
97%, solid
Synonyme(s) :
TBTA
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A propos de cet article
Formule empirique (notation de Hill) :
C30H30N10
Numéro CAS:
Poids moléculaire :
530.63
UNSPSC Code:
12161600
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Tris[(1-benzyl-1H-1, 2, 3-triazol-4-yl)methyl]amine, 97%
Quality Level
assay
97%
form
solid
reaction suitability
reagent type: ligand
reaction type: click chemistry
mp
132-143 °C
storage temp.
−20°C
SMILES string
C(N(Cc1cn(Cc2ccccc2)nn1)Cc3cn(Cc4ccccc4)nn3)c5cn(Cc6ccccc6)nn5
InChI
1S/C30H30N10/c1-4-10-25(11-5-1)16-38-22-28(31-34-38)19-37(20-29-23-39(35-32-29)17-26-12-6-2-7-13-26)21-30-24-40(36-33-30)18-27-14-8-3-9-15-27/h1-15,22-24H,16-21H2
InChI key
WKGZJBVXZWCZQC-UHFFFAOYSA-N
Application
A polytriazolylamine ligand which stabilizes Cu(I) towards disproportionation and oxidation thus enhancing its catalytic effect in the azide-acetylene cycloaddition.
hcodes
Hazard Classifications
Aquatic Chronic 4
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Laurie D Cohen et al.
PloS one, 8(5), e63191-e63191 (2013-05-10)
Chemical synapses contain multitudes of proteins, which in common with all proteins, have finite lifetimes and therefore need to be continuously replaced. Given the huge numbers of synaptic connections typical neurons form, the demand to maintain the protein contents of
Qian Wang et al.
Journal of the American Chemical Society, 125(11), 3192-3193 (2003-03-13)
The copper-catalyzed cycloaddition reaction between azides and alkynes functions efficiently in aqueous solution in the presence of a tris(triazolyl)amine ligand. The process has been employed to make rapid and reliable covalent connections to micromolar concentrations of protein decorated with either
Xiangyu Zhang et al.
Therapeutic advances in medical oncology, 12, 1758835920947976-1758835920947976 (2020-10-01)
Aspirin has recently emerged as an anticancer drug, but its therapeutic effect on lung cancer has been rarely reported, and the mechanism of action is still unclear. Long-term use of celecoxib in large doses causes serious side effects, and it