719897
Resomer® RG 502 H, Poly(D,L-lactide-co-glycolide)
acid terminated, viscosity 0.16-0.24 dL/g
Synonyme(s) :
PLGA
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A propos de cet article
Formule linéaire :
[C3H4O2]x[C2H2O2]y
Numéro CAS:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
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O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChI key
LCSKNASZPVZHEG-UHFFFAOYSA-N
form
amorphous
feed ratio
lactide:glycolide 50:50
degradation timeframe
<3 months
viscosity
0.16-0.24 dL/g
transition temp
Tg 42-46 °C
storage temp.
2-8°C
Quality Level
Catégories apparentées
Application
Poly(D,L-lactide-co-glycolide) (PLGA) canbe used:
- In the formulation ofa non-aqueous drug delivery system for H2S donors to aid thesustained release of the drug.
- To prepare a polymer blend containing Ganciclovir-loaded microspheresdispersed in PLGA–PEG–PLGA polymer gel. This formulation can be used as asustained delivery system for Ganciclovir drug.
Legal Information
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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The purpose of this work is to develop empirical equations for describing the in vitro ganciclovir (GCV) release from PLGA microspheres and also to develop and characterize a formulation containing GCV loaded PLGA microspheres dispersed in thermogelling PLGA-PEG-PLGA polymer gel.
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