79380
Phosgene solution
~20% in toluene
Synonyme(s) :
Carbon oxychloride, Carbonyl chloride, Phosgen
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
Formule linéaire :
COCl2
Numéro CAS:
Poids moléculaire :
98.92
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1098367
Form:
solution
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderform
solution
Quality Level
reaction suitability
reaction type: Carbonylations
concentration
~20% in toluene
impurities
≤300 mg/kg benzene
functional group
chloro
storage temp.
2-8°C
SMILES string
ClC(Cl)=O
InChI
1S/CCl2O/c2-1(3)4
InChI key
YGYAWVDWMABLBF-UHFFFAOYSA-N
General description
Phosgene is an organic chemical compound widely used as a chlorinating agent, carbonylating agent, and dehydrating agent in organic synthesis for the synthesis of various compounds.
Application
Phosgene solution (~20% in toluene) can be used as a reagent in the synthesis of multiblock copolymers via multiple coupling reactions. It is also used in the activation of the hydroxyl groups in poly(ethylene glycol) diol (PEG diol) to synthesize linear multifunctional poly(ethylene glycol).
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Repr. 2 - Skin Corr. 1B - STOT SE 1 Inhalation - STOT SE 3
target_organs
Central nervous system, Lungs
Classe de stockage
3 - Flammable liquids
wgk
WGK 3
flash_point_f
39.2 °F - closed cup
flash_point_c
4 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
J P Wyatt et al.
Journal of accident & emergency medicine, 12(3), 212-213 (1995-09-01)
Phosgene is a highly toxic gas to which some workers may be occupationally exposed. This case report demonstrates the possibility of refrigeration workers suffering phosgene poisoning after heating certain chlorinated fluorocarbons ('freons'). The need to suspect phosgene exposure and observe
O Gyllenhaal et al.
Journal of chromatography, 435(2), 259-269 (1988-01-08)
The use of phosgene as a derivatizing agent for bifunctional compounds prior to gas and liquid chromatographic analysis is reviewed. Applications include gas chromatographic determinations of metoprolol and its metabolites in biological fluids, enantiomeric separations of beta-blocking drugs and sympathomimetic
Alfred M Sciuto et al.
Inhalation toxicology, 16(8), 565-580 (2004-06-19)
A series of studies was performed to address treatment against the former chemical warfare edemagenic gas phosgene. Both in situ and in vivo models were used to assess the efficacy of postexposure treatment of phosgene-induced lung injury using clinically existing