850217
3,4-Dihydroxyphenylacetic acid
98%
Synonyme(s) :
DOPAC, Homoprotocatechuic acid
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A propos de cet article
Formule linéaire :
(HO)2C6H3CH2CO2H
Numéro CAS:
Poids moléculaire :
168.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-024-1
Beilstein/REAXYS Number:
2211017
MDL number:
Assay:
98%
Form:
powder
Service technique
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Laissez-nous vous aiderQuality Level
assay
98%
form
powder
mp
127-130 °C (lit.)
solubility
water: soluble 50 mg/mL, clear, almost colorless
functional group
carboxylic acid
SMILES string
OC(=O)Cc1ccc(O)c(O)c1
InChI
1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChI key
CFFZDZCDUFSOFZ-UHFFFAOYSA-N
General description
3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.
Application
3,4-Dihydroxyphenylacetic acid may be employed as ligand in the preparation of Mo(VI) complexes.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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B H Westerink et al.
European journal of pharmacology, 38(2), 281-291 (1976-08-01)
A concurrent semi-automatic fluorometric assay technique for 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), is described. The method is based on a rapid manually performed isolation of DOPAC and HVA on small columns of Sephadex G-10 followed by an automated
Simultaneous mass fragmentographic determination of 3, 4-dihydroxyphenylacetic acid and 4 hydroxy-3-methoxyphenylacetic acid in brain tissue.
F A Wiesel et al.
Journal of neural transmission, 35(4), 319-326 (1974-01-01)
A Y Deutch et al.
Brain research, 333(1), 143-146 (1985-04-29)
The effects of stress on dopamine (DA) metabolism in the mesencephalic DA cell body areas and DA terminal field regions were examined. Both mild footshock stress and exposure to a neutral stimulus previously paired with footshock resulted in a selective