P6801
Sodium phosphonoformate tribasic hexahydrate
Synonyme(s) :
Foscarnet, Phosphonoformic acid trisodium salt hexahydrate
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A propos de cet article
Formule linéaire :
Na2O3PCO2Na · 6H2O
Numéro CAS:
Poids moléculaire :
300.04
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Form:
powder
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powder
Quality Level
SMILES string
O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O
InChI
1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3
InChI key
ILRVASBWNRYBFD-UHFFFAOYSA-K
Gene Information
human ... POLA1(5422), POLD1(5424), POLG(5428)
rat ... Slc17a1(171080)
signalword
Warning
hcodes
Hazard Classifications
Muta. 2 - STOT RE 2
target_organs
Kidney,Bone
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Emily Rose et al.
Scientific reports, 9(1), 8798-8798 (2019-06-21)
How inorganic phosphate (Pi) homeostasis is regulated in Drosophila is currently unknown. We here identify MFS2 as a key Pi transporter in fly renal (Malpighian) tubules. Consistent with its role in Pi excretion, we found that dietary Pi induces MFS2
Tadashi Kato et al.
Calcified tissue international, 104(2), 201-206 (2018-10-21)
Nephronectin (Npnt), an extracellular matrix protein, is known to be a ligand of integrin α8β1, and it has also been known to play critical roles as various organs. In the present study, elevated extracellular inorganic phosphate (Pi) strongly inhibited the
Sampada Chande et al.
Scientific reports, 10(1), 3069-3069 (2020-02-23)
Low blood phosphate (Pi) reduces muscle function in hypophosphatemic disorders. Which Pi transporters are required and whether hormonal changes due to hypophosphatemia contribute to muscle function is unknown. To address these questions we generated a series of conditional knockout mice