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Merck

830845P

Avanti

14:0 PA

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-ditetradecanoyl-sn-glycero-3-phosphate (sodium salt); DMPA; PA(14:0/14:0)

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A propos de cet article

Formule empirique (notation de Hill) :
C31H60O8PNa
Numéro CAS:
Poids moléculaire :
614.77
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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description

1,2-dimyristoyl-sn-glycero-3-phosphate (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (830845P-200mg), pkg of 1 × 25 mg (830845P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCC)O

InChI

1S/C31H61O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-30(32)37-27-29(28-38-40(34,35)36)39-31(33)26-24-22-20-18-16-14-12-10-8-6-4-2;/h29H,3-28H2,1-2H3,(H2,34,35,36);/q;+1/p-1/t29-;/m1./s1

InChI key

UBSPGYHFNIKQIP-XXIQNXCHSA-M

General description

Phosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D. 14:0 PA/a negatively charged 1,2-dimyristoyl-sn-glycero-3-phosphate (DMPA) carries a phosphoric acid head group.

Application

14:0 PA may be used to prepare liposomes. It may also be used as a phospholipid (PL) standard to quantify phosphatidic acid (PA).

Biochem/physiol Actions

Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid.

Packaging

5 mL Amber Glass Screw Cap Vial (830845P-200mg)
5 mL Amber Glass Screw Cap Vial (830845P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


Classe de stockage

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Consulter la Bibliothèque de documents



Encapsulation and release of a hydrophobic drug from hydroxyapatite coated liposomes
Xu Q, et al.
Biomaterials, 28(16), 2687-2694 (2007)
Extraction and profiling of plant polar glycerol lipids
Liu, Yu and Wang, Xuemin
Bio-protocol (2016)
Wenjie Wang et al.
The journal of physical chemistry. B, 116(24), 7213-7220 (2012-05-23)
Although a minor component of the lipidome, phosphatidic acid (PA) plays a crucial role in nearly all signaling pathways involving cell membranes, in part because of its variable electrical charge in response to environmental conditions. To investigate how charge is