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Merck

850335C

Avanti

12:0 PC (DLPC)

Avanti Research - A Croda Brand

Synonyme(s) :

1,2-didodecanoyl-sn-glycero-3-phosphocholine; DLPC; PC(12:0/12:0)

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A propos de cet article

Formule empirique (notation de Hill) :
C32H64NO8P
Numéro CAS:
Poids moléculaire :
621.83
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Nom du produit

12:0 PC (DLPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850335C-25mg), pkg of 1 × 20 mL (850335C-500mg), pkg of 2 × 4 mL (850335C-200mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850335C

concentration

10 mg/mL (850335C-25mg), 25 mg/mL (850335C-200mg), 25 mg/mL (850335C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@@H](OC(=O)CCCCCCCCCCC)COC(=O)CCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C32H64NO8P/c1-6-8-10-12-14-16-18-20-22-24-31(34)38-28-30(29-40-42(36,37)39-27-26-33(3,4)5)41-32(35)25-23-21-19-17-15-13-11-9-7-2/h30H,6-29H2,1-5H3/t30-/m0/s1

InChI key

IJFVSSZAOYLHEE-PMERELPUSA-N

General description

The mucosal layer of the colon has phosphatidylcholine (PC). PCs carry fatty acids in the sn-1 and sn-2 positions, that are covalently attached to a glycerol through ester bonds.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

12:0 PC (DLPC/1,2-dilauroyl-sn-glycero-3-phosphocholine) may be used as a standard to quantify phosphatidylcholine. It has also been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

Biochem/physiol Actions

Phosphatidylcholine (PC) has the ability to block the penetrance of bacteria by acting as a surfactant.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850335C-500mg)
5 mL Clear Glass Sealed Ampule (850335C-200mg)
5 mL Clear Glass Sealed Ampule (850335C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Classe de stockage

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash



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Consulter la Bibliothèque de documents



Extraction and profiling of plant polar glycerol lipids
Liu Y and Wang X
Bio-protocol, 6, 1849e-1849e null
Comprehensive untargeted lipidomic analysis using core
Narvaaez R, et al.
Journal of Chromatography A, 1440, 123-134 null
John P Kowalski et al.
Chemical research in toxicology, 32(12), 2488-2498 (2019-12-05)
Cytochrome P450 4B1 (CYP4B1) has been explored as a candidate enzyme in suicide gene systems for its ability to bioactivate the natural product 4-ipomeanol (IPO) to a reactive species that causes cytotoxicity. However, metabolic limitations of IPO necessitate discovery of