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Merck

LM1503

Avanti

21:0-22:6 PI

Avanti Research - A Croda Brand

Synonyme(s) :

1-heneicosanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)

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A propos de cet article

Formule empirique (notation de Hill) :
C52H92NO13P
Numéro CAS:
Poids moléculaire :
970.26
UNSPSC Code:
12352211
NACRES:
NA.25
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form

methanol solution

packaging

pkg of 1 × 1 mL (LM1503-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COC(CCCCCCCCCCCCCCCCCCCC)=O.[NH4+]

Application

21:0-22:6 PI or 1-heneicosanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) has been used as an internal standard for phospholipid quantification using electrospray ionization tandem mass spectrometry (ESI-MS/MS) and for lipid quantification using liquid chromatography mass spectrometry (LC-MS).

Packaging

2 mL Amber Glass Sealed Ampule (LM1503-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup



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Christian Klose et al.
The Journal of biological chemistry, 285(39), 30224-30232 (2010-07-22)
The lipid raft concept proposes that biological membranes have the potential to form functional domains based on a selective interaction between sphingolipids and sterols. These domains seem to be involved in signal transduction and vesicular sorting of proteins and lipids.
Dharmaraja Allimuthu et al.
Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced