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Merck

C-045

Cannabidiol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

CBD

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A propos de cet article

Formule empirique (notation de Hill) :
C21H30O2
Numéro CAS:
13956-29-1
Poids moléculaire :
314.46
NACRES:
NA.24
PubChem Substance ID:
329774791
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00869597

Principaux documents

Voir toute la documentation
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Nom du produit

Cannabidiol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

SMILES string

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

cannabis testing
cannabis testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... CNR1(1268)

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Catégories apparentées

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Determination of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
  • Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) based technique to measure cannabidiol, ∆9-tetrahydrocannabinol, and its metabolites in whole blood samples obtained from rats administered a high dose of cannabidiol
  • Simultaneous determination of cannabidiol and tetrahydrocannabinol in different hemp oil-containing products using isocratic RP-HPLC coupled with UV detection
  • Multi-analysis of hair samples for Δ9-tetrahydrocannabinol, cannabinol, and cannabidiol by liquid-liquid extraction (LLE) followed by gas chromatography-mass spectrometry based quantification
  • Ultrasound-assisted extraction of cannabidiol from three different commercial topical products followed by GC-MS based determination

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

General description

The Certified Spiking Solution® is suitable for cannabidiol testing by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.

Cannabidiol (CBD) is one of the important cannabinoids found in plants of the Cannabaceae family known for its non-psychoactive properties. It forms upon the decarboxylation of its precursor cannabidiolic acid in the presence of light or heat. It shows various therapeutic properties, such as antioxidative, anti-inflammatory, antimicrobial, neuroprotective, anxiolytic, and anticonvulsant.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
Antonio Waldo Zuardi
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 30(3), 271-280 (2008-10-04)
The aim of this review is to describe the historical development of research on cannabidiol. This review was carried out on reports drawn from Medline, Web of Science and SciELO. After the elucidation of the chemical structure of cannabidiol in
Antonio Waldo Zuardi et al.
Current pharmaceutical design, 18(32), 5131-5140 (2012-06-22)
Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is the main compound of the Cannabis Sativa responsible for most of the effects of the plant. Another major constituent is cannabidiol (CBD), formerly regarded to be devoid of pharmacological activity. However, laboratory rodents and human studies have
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