C-046
Cannabinol solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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A propos de cet article
Formule empirique (notation de Hill) :
C21H26O2
Numéro CAS:
Poids moléculaire :
310.43
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
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Laissez-nous vous aiderInChI key
VBGLYOIFKLUMQG-UHFFFAOYSA-N
InChI
1S/C21H26O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9-13,22H,5-8H2,1-4H3
SMILES string
CCCCCc1cc(O)c-2c(OC(C)(C)c3ccc(C)cc-23)c1
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
cannabis testing
cannabis testing
format
single component solution
storage temp.
−20°C
Quality Level
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General description
The Certified Spiking Solution® is suitable for cannabinol testing by HPLC, GC/MS or LC-MS/MS methods in forensic analysis, clinical toxicology, urine drug testing, and Cannabis potency or impurity profiling testing applications.
Cannabinol is a phytocannabinoid that belongs to the class of C21 terpenophenolic compounds. Found in the cannabis plant it is a metabolite of Δ9-THC, the main psychoactive component of cannabis. Cannabinol is also the primary product of THC degradation from exposure to air and light.
Cannabinol is a phytocannabinoid that belongs to the class of C21 terpenophenolic compounds. Found in the cannabis plant it is a metabolite of Δ9-THC, the main psychoactive component of cannabis. Cannabinol is also the primary product of THC degradation from exposure to air and light.
Application
The Certified Reference Material (CRM) in solution can also be used as follows:
- Estimation of four cannabinoids from an oil matrix using reversed-phase high-performance liquid chromatography (RP-HPLC) combined with a diode array detector (DAD)
- Simultaneous analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
- Determination of eight cannabinoids in eight hemp samples and 12 forensic cannabis samples using reversed phase-high-pressure liquid chromatography (RP-HPLC) in combination with UV detector
- Analysis of dried marijuana flowers to measure the amount of nine cannabinoids by high-performance liquid chromatography (HPLC) along with UV detection
- Development and validation of an ultra high-performance liquid chromatographic (UHPLC) method coupled to photodiode array and mass spectrometry detectors to determine 11 cannabinoids in various Cannabis Sativa samples
- Quantitative analysis of 17 cannabinoids in cannabis and hemp samples by LC-MS/MS following their liquid-solid extraction following AOAC and ASTM guidelines for cannabis and hemp matrices
Features and Benefits
- Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
- Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
- Rigorously tested through real-time stability studies to ensure accuracy and shelf life
- Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
- Flame sealed under argon into ampoules for long-term shelf life
- Offered in a convenient, DEA-exempt format to improve laboratory efficiency
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
Classe de stockage
3 - Flammable liquids
wgk
WGK 2
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Dayong Lee et al.
Clinical chemistry, 57(8), 1127-1136 (2011-06-17)
Oral fluid (OF) is an accepted alternative biological matrix for drug treatment, workplace, and DUID (driving under the influence of drugs) investigations, but establishing the cannabinoid OF detection window and concentration cutoff criteria are important. Cannabinoid concentrations were quantified in
Satoshi Yamaori et al.
Biochemical pharmacology, 79(11), 1691-1698 (2010-02-02)
Inhibitory effects of Delta(9)-tetrahydrocannabinol (Delta(9)-THC), cannabidiol (CBD), and cannabinol (CBN), the three major constituents in marijuana, on catalytic activities of human cytochrome P450 (CYP) 1 enzymes were investigated. These cannabinoids inhibited 7-ethoxyresorufin O-deethylase activity of recombinant CYP1A1, CYP1A2, and CYP1B1
Michelle L Holland et al.
European journal of pharmacology, 591(1-3), 128-131 (2008-07-16)
The ATP-binding cassette (ABC) transporter ABCC1, or multidrug resistance-related protein 1 (MRP1) is implicated in Phase II metabolism and multidrug resistance as it effluxes substrate anticancer drugs. As cannabinoids inhibit two related ABC transporters, P-glycoprotein and ABCG2, here we examined
Krishna Prasad Bastola et al.
Planta medica, 73(3), 273-275 (2007-03-14)
Cannabinoids, the main constituents of the cannabis plant, are being increasingly studied for their medicinal properties. Cannabinolic acid (CBNA; 1) was synthesized from tetrahydrocannabinolic acid (THCA; 2), a major constituent of the cannabis plant, by aromatization using selenium dioxide mixed
F Van der Kooy et al.
Inhalation toxicology, 21(2), 87-90 (2008-10-16)
Medicinal cannabis has attracted a lot of attention in recent times. Various forms of administration are used, of which smoking is very common but the least desirable. Smoking cannabis generates a large amount of unwanted side products, of which carcinogenic
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