C-051
Caffeine solution
1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
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A propos de cet article
Numéro CAS:
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
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Laissez-nous vous aiderInChI key
RYYVLZVUVIJVGH-UHFFFAOYSA-N
InChI
1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
SMILES string
CN1C(=O)N(C)c2ncn(C)c2C1=O
grade
certified reference material
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in methanol
technique(s)
gas chromatography (GC): suitable, liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
Quality Level
Gene Information
human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
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General description
This Snap-N-Spike® Reference Solution is suitable for use in LC/MS or GC/MS applications from clinical toxicology to dietary supplement testing.
Caffeine belongs to the class of active alkaloid compounds, mainly found in the leaves, fruits, and seeds of about 63 plant species. Coffee beans are the primary source of caffeine, in addition to tea leaves, chocolates, and energy drinks soft drinks. It is a central nervous system stimulant and acts by increasing alertness and reducing sleep.
Caffeine belongs to the class of active alkaloid compounds, mainly found in the leaves, fruits, and seeds of about 63 plant species. Coffee beans are the primary source of caffeine, in addition to tea leaves, chocolates, and energy drinks soft drinks. It is a central nervous system stimulant and acts by increasing alertness and reducing sleep.
Application
The Certified Reference Material (CRM) in solution can also be used as follows:
- To determine caffeine content in an aqueous solution of green coffee beans by two methods based on Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) and fluorescence spectrophotometry
- Extraction of caffeine by automated homogeneous liquid-liquid microextraction (A-HLLME) from five different beverage samples for its quantification by high-performance liquid chromatography combined with UV detection
- Simultaneous estimation of caffeine and chlorogenic acids in ground green coffee samples by a UV/Vis spectrometric method
- Multi-residue determination of caffeine and paracetamol by square-wave voltammetry using poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode (poly(AHNSA)/GCE in coca-cola, pepsi, and tea samples
- Cyclic voltammetric and differential pulse voltammetric based detection and quantitative analysis of paracetamol, tryptophan, and caffeine, both separately and simultaneously, using an electrochemical sensor founded on tin sulfide (SnS)-titanium dioxide (TiO2)-graphene oxide (GO) composite modified glassy carbon electrode
Features and Benefits
- Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
- Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
- Rigorously tested through real-time stability studies to ensure accuracy and shelf life
- Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
- Flame sealed under argon into ampoules for long-term shelf life
- Offered in a convenient, DEA-exempt format to improve laboratory efficiency
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Classe de stockage
3 - Flammable liquids
wgk
WGK 1
flash_point_f
49.5 °F - closed cup
flash_point_c
9.7 °C - closed cup
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Louise A Horrigan et al.
Pharmacology & therapeutics, 111(3), 877-892 (2006-03-17)
Caffeine is a member of the methylxanthine family of drugs, and is the most widely consumed behaviourally active substance in the western world. This article is focused on the impact of caffeine on immune function. In this regard, a number
Jonathan M Hodgson et al.
The American journal of clinical nutrition, 97(5), 943-950 (2013-04-05)
Measures of blood pressure variation have been associated with cardiovascular disease and related outcomes. The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated. We aimed to assess
Helena Hallström et al.
American journal of epidemiology, 178(6), 898-909 (2013-07-25)
High consumption of coffee has been suggested to reduce the risk of some late-onset diseases and death but also to contribute to the development of osteoporotic fractures. Results of previous fracture studies have been inconsistent, and a comprehensive study is
Lisa N Sharwood et al.
BMJ (Clinical research ed.), 346, f1140-f1140 (2013-03-21)
To determine whether there is an association between use of substances that contain caffeine and the risk of crash in long distance commercial vehicle drivers. Case-control study. New South Wales (NSW) and Western Australia (WA), Australia. 530 long distance drivers
Pierre Ayotte et al.
Environmental health perspectives, 113(10), 1318-1324 (2005-10-06)
The Lower North Shore region of the St. Lawrence River is home to a fish-eating population that displays an unusually high body burden of several organochlorines, including polychlorinated biphenyls (PCBs) and dioxin-like compounds (DLCs). We measured biomarkers indicative of liver
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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