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Merck

S-010

Sildenafil solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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A propos de cet article

Formule empirique (notation de Hill) :
C22H30N6O4S
Numéro CAS:
139755-83-2
Poids moléculaire :
474.58
NACRES:
NA.24
PubChem Substance ID:
329824411
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00867528

Principaux documents

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Nom du produit

Sildenafil solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

BNRNXUUZRGQAQC-UHFFFAOYSA-N

InChI

1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

SMILES string

O=C1NC(C2=C(OCC)C=CC(S(=O)(N3CCN(C)CC3)=O)=C2)=NC4=C1N(C)N=C4CCC

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... PDE5A(8654)

Catégories apparentées

General description

Sildenafil is a treatment for erectile dysfunction and pulmonary arterial hypertension. Sold under the trade name Viagra®, sildenafil has a history of abuse, including by athletes as a performance enhancing drug. This Certified Spiking Solution® is applicable for use in urine drug testing, sports testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Viagra is a registered trademark of Pfizer, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Classe de stockage

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Certificats d'analyse (COA)

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Deanna Wung
International journal of pharmaceutical compounding, 17(1), 24-27 (2013-05-01)
The drugs tadalafil and sildenafil share the same mechanism. Although more research is necessary to solidify the recommendation of the routine use of tadalafil, human and dog data combined with pharmacokinetic data suggest that dogs may be safely treated for
[Yesterday, Viagra was a medication].
Jean-Yves Nau
Revue medicale suisse, 9(392), 1396-1397 (2013-07-26)
G Rocha et al.
Minerva pediatrica, 65(3), 271-278 (2013-05-21)
Over the last two decades, new therapies have emerged for the management of congenital diaphragmatic hernia (CDH). The aim of this paper was to review our experience in the management of newborns diagnosed with CDH over a 14-year period. Review
Hyerang Roh et al.
Clinical therapeutics, 35(3), 205-214 (2013-03-19)
An orally disintegrating film (ODF) formulation of sildenafil was recently developed in Korea. This formulation is expected to enhance dosing convenience and increase patient compliance while yielding pharmacokinetics comparable to those of the conventional film-coated tablet (FCT) formulation. The goal
Udomsak Wijitsettakul et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96(6), 683-688 (2013-08-21)
To evaluate the efficacy and safety of Elonza (generic product of sildenafil) 100 mg, a phosphodiesterase type 5 (PDE5) inhibitor, in Thai men with erectile dysfunction (ED). This prospective, Cohort study was conducted for eight weeks. Two hundred ten male
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