04-118
Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit monoclonal
culture supernatant, Upstate®
Synonyme(s) :
H4K5Ac, Histone H4 (acetyl K5)
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A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
vertebrates, human
Application:
WB
Citations:
14
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Laissez-nous vous aiderbiological source
rabbit
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
monoclonal
species reactivity
vertebrates, human
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
acetylation (Lys5)
Gene Information
human ... H4C1(8359)
General description
11kDa
Immunogen
Peptide corresponding to Histone H4 containing the sequence [GRG-AcK-GGK] on which Lys5 is acetylated.
Application
Detect acetyl-Histone H4 (Lys5) using this Anti-acetyl-Histone H4 (Lys5) Antibody, rabbit validated for use in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Biochem/physiol Actions
Recognizes Histone H4 when acetylated on Lys5.
Physical form
100 μL of rabbit monoclonal IgG cell culture supernatant in 0.1% sodium azide.
Preparation Note
2 years at -20°C from date of shipment
Analysis Note
Routinely evaluated by immunoblot.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Classe de stockage
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificats d'analyse (COA)
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Haipeng Guan et al.
Nature, 620(7974), 669-675 (2023-07-20)
Context-dependent dynamic histone modifications constitute a key epigenetic mechanism in gene regulation1-4. The Rpd3 small (Rpd3S) complex recognizes histone H3 trimethylation on lysine 36 (H3K36me3) and deacetylates histones H3 and H4 at multiple sites across transcribed regions5-7. Here we solved
S Ono et al.
Journal of experimental & clinical cancer research : CR, 21(3), 377-382 (2002-10-19)
Acetylation of core histones is closely linked to transcriptional activation of various genes. The acetylation levels of nucleosomal histones can be modified through a balance of histone acetyltransferases and deacetylases. To elucidate the role of histone acetylation in human gastric
RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation.
Carey, Michael, et al.
Molecular Cell, 24, 481-487 (2006)
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 04-118 | 04053252320996 |