05-1424
Anti-Endoglin Antibody, clone P3D1
clone P3D1, from mouse
Synonyme(s) :
CD105, Ancillary TGF-beta Receptor
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
P3D1, monoclonal
Application:
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Species reactivity:
mouse, human
Citations:
10
Technique(s):
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
Uniprot accession no.:
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderService technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderNom du produit
Anti-Endoglin Antibody, clone P3D1, clone P3D1, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
P3D1, monoclonal
species reactivity
mouse, human
species reactivity (predicted by homology)
rat
technique(s)
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ENG(2022)
mouse ... Eng(13805)
rat ... Eng(497010)
Catégories apparentées
Analysis Note
Control
Jurkat cell lysate
Jurkat cell lysate
Routinely evaluated by Western Blot on Jurkat lysates.
Western Blot Analysis: 1:500 dilution of this lot detected ENDOGLIN on 10 μg of Jurkat lysates.
Western Blot Analysis: 1:500 dilution of this lot detected ENDOGLIN on 10 μg of Jurkat lysates.
Application
Anti-Endoglin Antibody, clone P3D1 is an antibody against Endoglin for use in WB, IH, IC, IP, FC, ELISA.
Immunohistochemistry: For use on acetone or paraformaldehyde fixed tissue.
ELISA: A previous lot of this antibody was used in ELISA.
Immunoprecipitation: A previous lot of this antibody was used in IP.
Immunocytochemistry: A previous lot of this antibody was used in IC.
Flow Cytometry: A previous lot of this antibody was used in FC.
Optimal working dilutions must be determined by the end user.
ELISA: A previous lot of this antibody was used in ELISA.
Immunoprecipitation: A previous lot of this antibody was used in IP.
Immunocytochemistry: A previous lot of this antibody was used in IC.
Flow Cytometry: A previous lot of this antibody was used in FC.
Optimal working dilutions must be determined by the end user.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Biochem/physiol Actions
Reacts with human endoglin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Endoglin is a homodimeric integral membrane glycoprotein comprised of 95 kDa subunit. Endoglin is a component of the TGF-B receptor system that functions as an ancillary receptor influencing binding of the Transforming Growth Factor beta (TGF-β) family ligands to signaling receptors. Endoglin binds TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. Endoglin is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta and is weakly expressed by stromalfibroblasts. It is also expressed by U937 cells and activated macrophages. Endoglin expression is up regulated on activated endothelium in tissues undergoing angiogenesis, such as in tumors, or in cases of wound healing or dermal inflammation.
~71 kDa
Immunogen
Human resting umbilical vein endothelial cells.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MAB2152
Physical form
Format: Purified
Purified
Purified mouse monoclonal IgG2a in 0.02M phosphate buffer, 0.25M sodium chloride, 0.1% sodium azide, pH 7.6
Preparation Note
Stable at 2-8°C for up to 1 year from date of receipt.
Vous ne trouvez pas le bon produit ?
Essayez notre Outil de sélection de produits.
Classe de stockage
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Nicole M Valenzuela et al.
Journal of immunology (Baltimore, Md. : 1950), 190(12), 6635-6650 (2013-05-22)
Ab-mediated rejection (AMR) of solid organ transplants is characterized by intragraft macrophages. It is incompletely understood how donor-specific Ab binding to graft endothelium promotes monocyte adhesion, and what, if any, contribution is made by the Fc region of the Ab.
Snail1 controls TGF-? responsiveness and differentiation of mesenchymal stem cells.
Batlle, R, et al.
Oncogene (2012)
Lulwah Aldabbous et al.
Arteriosclerosis, thrombosis, and vascular biology, 36(10), 2078-2087 (2016-07-30)
Inflammation and dysregulated angiogenesis are features of endothelial dysfunction in pulmonary hypertension. Neutrophil extracellular traps (NETs), produced by dying neutrophils, contribute to pathogenesis of numerous vascular disorders but their role in pulmonary hypertension has not been studied. We sought evidence
Takuya Tokunaga et al.
The American journal of sports medicine, 43(10), 2411-2422 (2015-08-28)
Fibroblast growth factor (FGF)-2 has the potential to enhance tendon-to-bone healing after rotator cuff (RC) injury. FGF-2 stimulates tenogenic differentiation of progenitors to improve the biomechanical strength and histological appearance of repaired RCs in rats. Controlled laboratory study. Adult male
Claus Kordes et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 31(2-3), 290-304 (2013-03-15)
Hematopoiesis can occur in the liver, when the bone marrow fails to provide an adequate environment for hematopoietic stem cells. Hepatic stellate cells possess characteristics of stem/progenitor cells, but their contribution to hematopoiesis is not known thus far. Isolated hepatic
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| 05-1424 | 04053252274862 |
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
Contacter notre Service technique